Flocculated suspension of megestrol acetate

  • US 6,268,356 B1
  • Filed: 10/12/1999
  • Issued: 07/31/2001
  • Est. Priority Date: 04/20/1998
  • Status: Expired due to Term
First Claim
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1. A method of treating a neoplastic condition comprising administering to a subject suffering from said condition an oral pharmaceutical composition in the form of a stable flocculated suspension in water capable of being redispersed after being allowed to settle at 40°

  • C. and 75% relative humidity for a period of three months, said composition comprising;

    (a) about 10 to 200 mg per ml micronized megestrol acetate;

    (b) about 10 to 40% by weight of at least one compound selected from the group consisting of polyethylene glycol, propylene glycol, glycerol, and sorbitol; and

    (c) about 0.0001 to 0.03% by weight of a surfactant, wherein polysorbate and polyethylene glycol are not simultaneously present in said composition.

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