Multi-well rotary synthesizer

  • US 6,270,730 B1
  • Filed: 06/16/1998
  • Issued: 08/07/2001
  • Est. Priority Date: 06/16/1998
  • Status: Expired due to Term
First Claim
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1. A synthesizer for foraging a polymer chain by sequentially adding monomer units found in one of a plurality of reagent solutions, the synthesizer comprising:

  • a. a first vial and a second vial, each for holding a selective one or more of the plurality of reagent solutions during synthesis;

    b. means for dispensing configured for dispensing the selective one or more of the plurality of reagent solutions into the first and second vials;

    c. a cartridge configured for holding the first vial and the second vial;

    d. a drain plate coupled to the cartridge including a first collection area having a first drain configured to collect material from the first vial and a second collection area having a second drain configured to collect material from the second vial; and

    e. means for expelling material from a selective ore of the first and second vials, including means for collecting configured for selectively engaging one of the first drain and the second drain corresponding to the selective one of the first and second vials and thereby purging material from the selective one of the first vial and the second vial when the means for collecting engages the selective one of the first drain and the second drain, wherein in order to engage the first drain and the second drain, a selective one or both of the means for collecting and the selective one of the first drain and the second drain are moved in relation to each other.

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