Method and portable colposcope useful in cervical cancer detection

• US 6,277,067 B1
• Filed: 04/04/1997
• Issued: 08/21/2001
• Est. Priority Date: 04/04/1997
• Status: Expired due to Fees

• Current Assignee: MedTech Research SA
• Original Assignee: MedTech Research SA
• Inventors: Blair, Kerry L.
• Primary Examiner(s): Hirsch, Paul J.
• Application Number:
  US08/832,944
• Time in Patent Office: 1,600 Days
• Field of Search: 600/135, 600/167, 600/160, 600/105, 600/109, 600/476, 348/68, 348/71, 348/77
• US Class Current: 600/167
• CPC Class Codes: A61B 1/0004 for electronic operation
• CPC Class Codes: A61B 1/00048 Constructional features of the display
• CPC Class Codes: A61B 1/0005 combining images e.g. side-by-side, superimposed or tiled
• CPC Class Codes: A61B 1/042 characterised by a proximal camera, e.g. a CCD camera
• CPC Class Codes: A61B 1/0623 for off-axis illumination
• CPC Class Codes: A61B 1/0676 at distal tip of an endoscope
• CPC Class Codes: A61B 1/303 for the vagina, i.e. vaginoscopes

Abstract

A method and portable apparatus for the visual examination and grading of cervical epithelium by means of a hand-held colposcopy assembly capable of producing a digital image of the cervix. The present invention enables real-time imaging and archiving of images of the entire cervix for the purpose of detecting cancerous and pre-cancerous tissue and by virtue of computerized image processing suggests an objective diagnosis of the cervical epithelium by means of a low cost, portable, hand-held digital colposcope.

Claims

1. A portable, cervical-cancer detection apparatus comprising a camera having fixed-focus optics, an optical axis associated with the fixed-focus optics, a focal point associated with the fixed-focus optics and lying a predetermined distance from the camera, the apparatus further comprising a processor, a display monitor, and first and second light sources attached to the apparatus and spaced from said optical axis of the camera, the light sources being co-planar with said optical axis and operable to emit first and second energy beams which produce first and second spots upon contacting cervical tissue of a patient, the first and second light sources being oriented so that the first and second energy beams intersect on said optical axis at the focal point of the camera, whereby as the apparatus is aimed at cervical tissue of the patient the first and second spots converge at the focal point thereby insuring that the cervical tissue is properly focused in the camera.

2. The apparatus according to claim 1 further comprising a housing, the housing containing the camera, the processor, the monitor, and first and second light sources.

3. The apparatus according to claim 2 wherein the apparatus is hand held and weighs less than five pounds.

4. The apparatus according to claim 2, wherein the camera is a digital camera operable to create at least first and second digital images, the digital images having substantially the same field of view, each digital image comprising an array of discrete digital image elements, each image element of each image having a spatially identical corresponding element in at least the other digital image, and wherein the apparatus further comprises strobe lights associated with the camera for illuminating the cervix with light pulses emitted from at least two locations, said strobe lights being operable to synchronize the emission of the pulses so that the cervix is illuminated with said first pulse for the creation of the first image and the cervix is illuminated with the second pulse for the creation of the second image, first glare and non-glare regions created by the first pulse in the first image, second glare and non-glare regions created by the second pulse in the second image, and wherein the processor includes digital processing means operable to create a substantially glare-free digital composite image by replacing the discrete digital elements of the glare region of one image with the corresponding discrete digital elements from the non-glare region of the other image.

5. A portable, cervical-cancer detection apparatus comprising, a digital camera having fixed-focus optics, an optical axis associated with the fixed-focus optics, a focal point associated with the fixed-focus optics and lying a predetermined distance from the camera, and first and second light sources attached to the apparatus and spaced from said optical axis of the camera, the light sources being co-planar with said optical axis and operable to emit first and second energy beams which produce first and second spots upon contacting cervical tissue of a patient, the first and second light sources being oriented so that the first and second energy beams intersect on said optical axis at the focal point of the camera, whereby as the apparatus is aimed at cervical tissue of the patient the first and second spots converge at the focal point thereby insuring that the cervical tissue is properly focused in the camera.

6. The apparatus according to claim 5, wherein said camera is located between the first and second light sources.

7. The apparatus according to claim 6, wherein the first and second light sources are spaced from said optical axis of the camera such that the distance of convergence and divergence of the first and second spots on the cervical tissue of the patient is less than the distance of movement of the camera along the optical axis toward and away from the cervical tissue.

8. The apparatus according to claim 6, wherein the focal point is positioned approximately 23 cm from the camera.

9. The apparatus according to claim 8, wherein the first and second light sources is set apart between 3.5 cm and 7.5 cm.

10. The apparatus according to claim 5, wherein the apparatus is sized to be hand-held and weigh less than five pounds.