Thin film radiation source
First Claim
1. A radiation delivery source, comprising:
- a substrate having at least a first side, wherein the substrate is a thin film layer which is an inflatable balloon; and
an isotope layer on at least the first side of the substrate, wherein said isotope layer comprises a metal salt or oxide, and at least one isotope.
3 Assignments
0 Petitions
Accused Products
Abstract
Disclosed is a thin film radiation source, which may be used to deliver a radioactive dose to a site in a body lumen. The source comprises a thin flexible substrate, and a layer of radioisotope attached thereto. The source may further comprise additional layers such as one or more tie layers disposed between the substrate and the radioisotope layer and one or more outer coating layers. In one embodiment, the source is wrapped around an inflatable balloon. Inflation of the balloon at a treatment site positions the source directly adjacent to the vessel wall, and allows irradiation of the site following or simultaneously with a balloon angioplasty, stent implantation, or stent sizing procedure.
186 Citations
112 Claims
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1. A radiation delivery source, comprising:
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a substrate having at least a first side, wherein the substrate is a thin film layer which is an inflatable balloon; and
an isotope layer on at least the first side of the substrate, wherein said isotope layer comprises a metal salt or oxide, and at least one isotope. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 18, 19, 20, 21, 22)
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16. A radiation delivery source, comprising:
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a substrate having at least a first side, wherein the substrate is a thin film layer which is an inflatable balloon;
a tie layer on at least the first side of the substrate; and
an isotope layer bound to the tie layer, wherein said isotope layer comprises a metal salt or metal oxide, and at least one isotope. - View Dependent Claims (17, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32)
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33. A radiation delivery source, comprising:
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a substrate having at least a first side, wherein the substrate is a porous thin film layer; and
an isotope layer on at least the first side of the substrate, wherein said isotope layer comprises a metal salt or metal oxide, at least one isotope. - View Dependent Claims (34, 35, 36, 37, 38, 39, 40, 41, 42, 43)
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44. A radiation delivery source, comprising:
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a substrate having at least a first side, wherein the substrate is a portion of an inflatable balloon; and
an isotope layer on at least the first side of the substrate, wherein said isotope layer comprises a metal salt or metal oxide, and at least one isotope. - View Dependent Claims (45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56)
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57. A radiation delivery source, comprising:
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a substrate having at least a first side, wherein the substrate is a porous thin film layer;
a tie layer on at least the first side of the substrate; and
an isotope layer bound to the tie layer, wherein said isotope layer comprises a metal salt or metal oxide, and at least one isotope. - View Dependent Claims (58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 72, 75, 76)
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69. A radiation delivery source, comprising:
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a substrate having at least a first side, wherein the substrate is a portion of an inflatable balloon;
a tie layer on at least the first side of the substrate; and
an isotope layer bound to the tie layer, wherein said isotope layer comprises a metal salt or metal oxide, and at least one isotope. - View Dependent Claims (70, 71, 73, 74, 77, 78, 79, 80, 81, 82)
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83. A radiation delivery source, comprising:
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a substrate having at least a first side, wherein the substrate is a thin film layer carried by an inflatable balloon; and
an isotope layer on at least the first side of the substrate, wherein said isotope layer comprises a metal salt or metal oxide, and at least one isotope. - View Dependent Claims (84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98)
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99. A radiation delivery source, comprising:
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a substrate having at least a first side, wherein the substrate is a thin film layer carried by an inflatable balloon;
a tie layer on at least the first side of the substrate; and
an isotope layer bound to the tie layer, wherein said isotope layer comprises a metal salt or metal oxide, and at least one isotope. - View Dependent Claims (100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112)
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Specification