Chicken GNRH analogs and uses thereof in regulation of fertility and pregnancy

  • US 6,323,179 B1
  • Filed: 10/15/1999
  • Issued: 11/27/2001
  • Est. Priority Date: 10/15/1999
  • Status: Expired due to Term
First Claim
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1. A Chicken II GnRH decapeptide analog, having the sequence p-Glu-His-Trp-Ser-His-Xaa1-Trp-Tyr-Pro-Xaa2, capable of binding to human chorionic, placental or ovarian GnRH receptors and active in the presence of a post-proline peptidase or an endopeptidase, said analog comprising a D-amino acid substitution at position 6 and an ethylamide or aza-Gly-amide substitution at position 10.

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