Sustained release delivery system
DCFirst Claim
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1. A sustained release delivery system, which comprises:
- an active therapeutic drug dispersed with a polymer matrix which is solubilized or suspended in a liquid medium;
wherein the polymer matrix consists of hyaluronic acid of salts thereof blended with a nonionic polymer selected from the group consisting of hydroxyethylcellulose, hydroxypropylcellulose and mixture thereof;
and wherein the molar ratio of the hyaluronic acid or salts thereof to the nonionic polymers 1;
0.5 to 2.0.
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Abstract
Sustained release compositions comprising a drug dispersed within a polymer matrix, methods of producing the same and treatments with the complex.
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11 Claims
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1. A sustained release delivery system, which comprises:
- an active therapeutic drug dispersed with a polymer matrix which is solubilized or suspended in a liquid medium;
wherein the polymer matrix consists of hyaluronic acid of salts thereof blended with a nonionic polymer selected from the group consisting of hydroxyethylcellulose, hydroxypropylcellulose and mixture thereof;and wherein the molar ratio of the hyaluronic acid or salts thereof to the nonionic polymers 1;
0.5 to 2.0.- View Dependent Claims (2, 3, 4, 5)
- an active therapeutic drug dispersed with a polymer matrix which is solubilized or suspended in a liquid medium;
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6. A sustained release delivery system, which comprises:
- a polymer matrix suspended of solubilized in a liquid medium, wherein the polymer matrix contains mucopolysaccharides and derivatives thereof, blended with a nonionic polymer selected from the group consisting of hydroxyethylcellulose, hydroxypropylcellulose and mixtures thereof, and wherein the molar ratio of the negative charged polymer to the nonionic polymer is 1;
0.5 to 2. - View Dependent Claims (7, 8, 9, 10, 11)
- a polymer matrix suspended of solubilized in a liquid medium, wherein the polymer matrix contains mucopolysaccharides and derivatives thereof, blended with a nonionic polymer selected from the group consisting of hydroxyethylcellulose, hydroxypropylcellulose and mixtures thereof, and wherein the molar ratio of the negative charged polymer to the nonionic polymer is 1;
Specification