Implantable glucose sensor

  • US 6,343,225 B1
  • Filed: 09/14/1999
  • Issued: 01/29/2002
  • Est. Priority Date: 09/14/1999
  • Status: Expired due to Term
First Claim
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1. An implantable sensor for sensing a concentration of an organic substrate, the sensor comprising:

  • a conductive electrode; and

    a stabilized enzyme emulsion in contact with the electrode, the enzyme emulsion comprising;

    an oxidase enzyme that quantitatively oxidizes the organic substrate;

    a water immiscible oxygen dissolving substance emulsified into intimate contact with the enzyme to provide oxygen; and

    a protein crosslinking agent to crosslink and insolubilize the enzyme forming a stabilized gel comprising crosslinked protein and particles of said oxygen dissolving substance.

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