Process of making an aqueous calcium carbonate suspension
First Claim
Patent Images
1. A method for neutrallizing excess stomach acid in a mammal in need thereof, which method comprises orally administering to said mammal an effective amount of a liquid antacid suspension having a formula comprising:
2 Assignments
0 Petitions
Accused Products
Abstract
The present invention relates to a high dosage calcium carbonate aqueous antacid pharmaceutical suspension for oral use, and methods of preparation.
43 Citations
14 Claims
-
1. A method for neutrallizing excess stomach acid in a mammal in need thereof, which method comprises orally administering to said mammal an effective amount of a liquid antacid suspension having a formula comprising:
-
2. A method for neutralizing excess stomach acid in a mammal in need thereof, which method comprises orally administering to said mammal an effective amount of a liquid antacid sispension of the formula comprising:
-
3. A method of preparing a stable aqueous antacid suspension for oral use with a pH of about 7.5 to about 8.7 which comprises:
-
a) adding to water an effective amount of calcium carbonate with mixing until the calcium carbonate is completely wetted and dispersed; and
b) adding to said mixture of part a) with stirring a suspending agent for a time sufficient to substantially coat said calcium carbonate, and to produce a suspension;
or alternately adding b) to a);
c) while stirring, titrating the suspension of part b) with a pH adjusting agent to provide a pH of about 6.4 to 7.0 to the aqueous antacid suspension; and
d) upon standing the suspension will equilibrate to a stable pH of about 7.5 to 8.7. - View Dependent Claims (4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
-
Specification