Rapid mapping of electrical activity in the heart

• US 6,400,981 B1
• Filed: 06/21/2000
• Issued: 06/04/2002
• Est. Priority Date: 06/21/2000
• Status: Expired due to Term

• Current Assignee: Biosense, Inc. (Cardinal Health, Inc.)
• Original Assignee: Biosense, Inc. (Cardinal Health, Inc.)
• Inventors: Govari, Assaf
• Primary Examiner(s): Layno, Carl
• Application Number:
  US09/598,862
• Time in Patent Office: 713 Days
• Field of Search: 600/508, 600/509, 600/510
• US Class Current: 600/509
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 5/06 Devices, other than using radiation, for detecting or locating foreign bodies for removing same A61B17/50 ; determining position of probes within or on the body of the patient
• CPC Class Codes: A61B 5/062 using magnetic field
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]

Abstract

A method for mapping electrical activity of a heart includes inserting a probe into a chamber of the heart, the probe including at least one position sensing device and a plurality of non-contact electrodes. Position coordinates of the electrodes are determined relative to an endocardial surface of the chamber, using the at least one position sensing device, and electrical potentials are measured at the determined position coordinates using the electrodes. Electrical potentials are computed at a plurality of points on the endocardial surface, using the measured potentials and the position coordinates, so as to generate a map of electrical activity over the endocardial surface based on the computed potentials.

Claims

1. A method for mapping electrical activity of a heart, comprising:

inserting a probe into a chamber of the heart, the probe comprising at least one position sensing device and a plurality of non-contact electrodes;

determining position coordinates of the electrodes relative to an endocardial surface of the chamber, using the at least one position sensing device;

measuring electrical potentials at the determined position coordinates using the electrodes;

computing electrical potentials at a plurality of points on the endocardial surface, using the measured potentials and the position coordinates by finding an electric dipole strength at each of the plurality of points on the endocardial surface, responsive to the measured potentials; and

generating a map of electrical activity over the endocardial surface based on the computed potentials.

2. A method according to claim 1, wherein inserting the probe comprises positioning the probe such that the non-contact electrodes make substantially no physical contact with the endocardial surface.

3. A method according to claim 2, wherein finding the electric dipole strength comprises modeling the measured electrical potentials as being due to a superposition of respective electric dipole fields generated at the plurality of points on the endocardial surface, responsive to the determined position coordinates of the electrodes relative to respective position coordinates of the points.

4. A method according to claim 3, wherein finding the electric dipole strength at each of the plurality of points comprises deriving a system of equations expressing the measured potentials as a function of the superposition of dipole fields, and inverting the equations.

5. A method according to claim 1, wherein computing the electrical potentials comprises acquiring a geometrical model of the endocardial surface, and finding a position of each of the electrodes relative to each of the plurality of points on the endocardial surface responsive to the geometrical model.

6. A method according to claim 5, wherein acquiring the geometrical model comprises using the probe to generate the geometrical model.

7. A method according to claim 6, wherein using the probe to generate the geometrical model comprises bringing a distal tip of the probe into contact with a plurality of locations on the endocardial surface so as to determine position coordinates of the locations using the position sensing device, and generating the model using the position coordinates of the locations.

8. Apparatus for mapping electrical activity of a heart, comprising:

a probe, having a distal end configured for insertion into a chamber of the heart, the probe comprising, in proximity to the distal end, at least one position sensing device and a plurality of non-contact electrodes;

a processor, coupled to the probe so as to determine position coordinates of the electrodes relative to an endocardial surface of the chamber, using the at least one position sensing device, and to measure electrical potentials at the determined position coordinates using the electrodes, so as to compute electrical potentials at a plurality of points on the endocardial surface, using the measured potentials and the position coordinates, wherein the processor is adapted to compute an electric dipole strength at each of the plurality of points, responsive to the measured potentials; and

a display, coupled to be driven by the processor so as to display a map of electrical activity over the endocardial surface based on the computed potentials.

9. Apparatus according to claim 8, wherein the plurality of non-contact electrodes comprise an array of electrodes disposed over a surface of the probe in proximity to the distal end, so as to measure the electrical potentials substantially without physical contact with the endocardial surface.

10. Apparatus according to claim 9, wherein the at least one position sensing device comprises a first position sensing device adjacent to the distal end of the probe and a second position sensing device in a position proximal to the first position sensing device and in proximity to the array of electrodes.

11. Apparatus according to claim 8, wherein the processor is adapted to model the measured electrical potentials as being due to a superposition of respective electric dipole fields generated at the plurality of points, responsive to the determined position coordinates of the electrodes relative to respective position coordinates of the points.

12. Apparatus according to claim 11, wherein the processor is adapted to find a system of equations expressing the measured potentials as a function of the superposition of dipole fields, and to compute the electric dipole strengths by inverting the equations.

13. Apparatus according to claim 8, wherein the processor is adapted to acquire a geometrical model of the endocardial surface, and to find a position of each of the electrodes relative to each of the plurality of points on the endocardial surface responsive to the geometrical model.

14. Apparatus according to claim 13, wherein the processor is adapted to generate the geometrical model using the probe.

15. Apparatus according to claim 14, wherein to generate the geometrical model, the distal end of the probe is brought into contact with a plurality of locations on the endocardial surface so as to determine position coordinates of the locations using the position sensing device, and wherein the processor is adapted to generate the model using the position coordinates of the locations.

16. Apparatus according to claim 8, including at least one contact electrode on the distal end of the catheter.

17. Apparatus according to claim 9, wherein the non-contact electrodes are ring electrodes.