Phosphonocephem derivatives, process for the preparation of the same, and use thereof

  • US 6,417,175 B1
  • Filed: 06/06/2000
  • Issued: 07/09/2002
  • Est. Priority Date: 12/19/1997
  • Status: Expired due to Term
First Claim
Patent Images

1. A compound of the formula:

  • embedded imagewherein R1 is a phosphono group;

    R2 is a hydrogen atom, an optionally substituted C1-6 alkyl group or a C3-5 cycloalkyl group;

    each of Q and X is a nitrogen atom or CH;

    Y is S;

    n is 0 or 1;

    one of R3 and R4 is a pyridinium group which may be substituted and the other is a hydrogen atom or a hydrocarbon group which may be substituted, or R3 and R4 taken together may form a quaternized nitrogen-containing heterocyclic ring which may be substituted, wherein when R3 and R4 are taken together, the group of the formula embedded imagewherein R5 is an optionally substituted hydrocarbon group;

    or salt thereof.

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