Method for reducing adverse effects of a human 70kDa mediator which results from endotoxin stimulation of macrophages

  • US 6,419,927 B1
  • Filed: 11/28/1994
  • Issued: 07/16/2002
  • Est. Priority Date: 09/08/1981
  • Status: Expired due to Fees
First Claim
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1. A method for treating an adverse effect in a human of the about 70 kDa mediator substance which results from endotoxin stimulation of macrophages and which has the biological activity of suppression of lipoprotein lipase activity, said method comprising administering an antibody specifically reactive with said about 70 kDa mediator in an amount effective to neutralize suppression of an anabolic enzyme selected from the group consisting of lipoprotein lipase, acetyl coA carboxylase and fatty acid synthetase, said suppression induced by said about 70 kDa mediator.

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