Method for monitoring insulin medication

• US 6,425,863 B1
• Filed: 02/28/2001
• Issued: 07/30/2002
• Est. Priority Date: 03/31/1998
• Status: Expired due to Term

• Current Assignee: Roche Diagnostics GmbH (Roche Holding AG)
• Original Assignee: Roche Diagnostics GmbH (Roche Holding AG)
• Inventors: Muller, Wilfried, Werner, Karl, Blasberg, Peter
• Primary Examiner(s): Shaver, Kevin
• Assistant Examiner(s): Natnithithadha, Navin
• Application Number:
  US09/646,848
• Time in Patent Office: 517 Days
• Field of Search: 600/365, 600/347, 600/316, 600/319, 600/300, 128/920, 128/921, 128/923
• US Class Current: 600/365
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: Y10S 128/92 Computer assisted medical diagnostics
• CPC Class Codes: Y10S 128/921 Diet management

Abstract

Method for monitoring insulin medication in which blood sugar values are determined before and after a meal. The difference between these measured values is plotted against a quotient calculated from the bread units ingested during the meal and the insulin units used to compensate for these bread units. Displaying many such points on a graph provides criteria for improving the insulin medication.

Claims

1. Method for monitoring the influence of insulin medication and meals of a user, the method comprising the steps of:

a) providing sets of data containing the following data;

a blood sugar value (BVi) determined before the meal,

a blood sugar value (BNi) determined after the meal,

bread units (BEi) ingested by the user during the meal, and

insulin units (Ii) administered to the user between the determination of the blood sugar values (BVi and BNi),

b) calculating blood sugar differences Δ

Bi from the blood sugar values (BVi and BNi) before and after the meal respectively for individual sets of data,

c) calculating a quotient Qi from the insulin units (Ii) and bread units (BEi),

d) plotting points Pi (Δ

Bi;

Qi) in a system of coordinates comprising a first coordinate for the blood sugar differences (Δ

Bi) and a second coordinate for the quotients (Qi),

e) outputting the coordinate system with the points (Pi) on an output device.

2. Method as claimed in claim 1, in which the blood sugar difference is calculated by an equation Δ

Bi=BNi−

BVi.

3. Method as claimed in claim 1, in which the quotient (Qi) is calculated by an equation Qi=Ii/BEi.

4. Method as claimed in claim 1, in which all blood sugar values BVi and BNi are determined before or after the same type of meal.

5. Method as claimed in claim 2, in which the meal is a type of meal selected from the group of breakfast, lunch and dinner.

6. Method as claimed in claim 1, in which the blood sugar values BVi are determined no more than 1 hour before the start of the meal and the blood sugar values BNi are determined at the latest before the next meal of the user.

7. Method as claimed in claim 1, wherein the output step includes displaying a specially labelled centre of concentration with the system of coordinates on the output device.

8. Method as claimed in claim 1 or 7, further comprising the step of determining a regression line from the points (Pi).

9. Method as claimed in claim 8, wherein the output step includes displaying the regression line together with the points (Pi) and the system of coordinates on the output device.

10. Method as claimed in claim 8, wherein the output step includes displaying the value of the regression line for Δ

Bi=O either graphically or numerically.

11. Method as claimed in claim 7, in which the first coordinates of the centre of concentration is shown qualitatively or quantitatively.

12. Method as claimed in claim 1, further comprising the step of checking whether the quotient (Qi) is positive and the plotting step includes selecting only sets of data for which the quotient (Qi) is positive.

13. Method as claimed in claim 1, further comprising the step of checking whether the quotient (Qi) is in the range of 0.1 to 10 and the plotting step includes selecting only sets of data are used for which this applies.

14. Method as claimed in claim 1, further comprising the step of checking whether the blood sugar value before the meal (BVi) is in the range of 80 to 180 mg/dl and the plotting step includes selecting only sets of data are used for which this applies.

15. Method as claimed in claim 1, further comprising the step of checking whether the blood sugar value before the meal (BVi) is in the range of 80 to 180 mg/dl and the quotient (Qi) is in the range of 0.1 to 10 and only sets of data are used for which this applies.

16. Device for monitoring the influence of insulin medication and meals of a user, the device comprising:

an input unit formed to receive sets of data containing

blood sugar values (BVi) determined before the meal,

blood sugar values (BNi) determined after the meal,

bread units (BEi) ingested during the meal,

insulin units (Ii) administered between the determination of the blood sugar values BVi and BNi,

a unit for calculating blood sugar differences Δ

Bi from the blood sugar values (BVi) and (BNi) before and after the meal respectively for individual sets of data,

a unit for calculating quotients (Qi) from insulin units (Ii) and bread units (BEi),

an output unit formed to display a graph of (Δ

Bi;

Qi) in a system of coordinates in which the first coordinates are the blood sugar differences (Δ

Bi) and the second coordinates are the quotients (Qi).

17. System for monitoring insulin medication comprising a device as claimed in claim 16 and a blood sugar measuring instrument.

18. System as claimed in claim 17, in which the device and the blood sugar measuring instrument are coupled together by a dataline such that the blood sugar measuring instrument can transmit blood sugar values to the device.

19. System as claimed in claim 18, in which the device and the blood sugar measuring instrument are accommodated in a common housing.

20. A device formed to monitor insulin medication as it relates to meals consumed by a user, the device comprising:

an input unit formed to receive data comprising blood sugar values (BVi) determined before the meal, blood sugar values (BNi) determined after the meal, bread units (BEi) ingested during the meal, and insulin units (Ii) administered between the determination of the blood sugar values (BVi) and (BNi),

a unit formed to calculate blood sugar differences (Δ

Bi) by an equation Δ

Bi=BNi−

BVi for individual sets of data,

a unit formed to calculate quotients (Qi) by an equation Qi=Ii/BEi, and

an output unit formed to display a system of coordinates in which the first coordinates are the blood sugar differences (Δ

Bi) and the second coordinates are the quotients (Qi).