Method of treating complex regional pain syndromes by electrical stimulation of the sympathetic nerve chain

• US 6,438,423 B1
• Filed: 01/25/2000
• Issued: 08/20/2002
• Est. Priority Date: 01/20/2000
• Status: Expired due to Term

• Current Assignee: Electrocore Technologies LLC
• Original Assignee: Electrocore Technologies LLC
• Inventors: Rezai, Ali R., Zonenshayn, Martin
• Primary Examiner(s): Jastrzab, Jeffrey R.
• Application Number:
  US09/490,617
• Time in Patent Office: 938 Days
• Field of Search: 607/43, 607/46, 607/68-75, 128/898
• US Class Current: 607/46
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/32 alternating or intermittent currents applying electric fields by inductive or capacitive coupling A61N1/40; microwave apparatus A61N5/02

Abstract

A method for treating complex regional pain syndromes by applying an oscillating electric field to appropriate sympathetic ganglia. The method includes the steps of inserting an electrode into the vicinity of the sympathetic ganglion, for example the stellate and upper thoracic ganglia, such that the necessary electric field may be applied to the ganglion. The necessary field oscillation frequency and strength, as well as other characteristics of the signal are determined individually for each patient. Continued driving of the pathological activity of the ganglion into the normal function is the long-term, reversible palatative remedy for the condition.

Claims

1. A method of interventionally and reversibly treating complex regional pain syndromes comprising:

implanting at least one electrode, having distal and proximal termini, such that the distal terminus is in the vicinity of the sympathetic chain;

coupling the proximal terminus of the at least one electrode to an electrical signal source;

applying an oscillating electric field to the sympathetic chain in a frequency range of 2 to 2500 Hz;

varying the frequency of the oscillating electric field until the symptoms of the pain syndrome have been demonstrably alleviated; and

continuing the application of the oscillating electric field.

2. The method as set forth in claim 1, wherein the vicinity of the sympathetic chain is adjacent to the stellate ganglion.

3. The method as set forth in claim 1, wherein said stimulation increases nerve activity.

4. The method as set forth in claim 1, wherein said stimulation decreases nerve activity.

5. The method as set forth in claim 1, wherein said step of applying said oscillating electric field comprises applying said oscillating electric field in a high frequency range of 50 to 2500 Hz.

6. The method as set forth in claim 1, wherein said step of applying said oscillating electric field comprises applying said oscillating electric field in a low frequency range of 2 to 100 Hz.

7. The method as set forth in claim 1, wherein the at least one electrode is a monopolar electrode and the application of the oscillating electric field is monopolar.

8. The method as set forth in claim 1, wherein the at least one electrode is a bipolar electrode and the application of the oscillating electric field is bipolar.

9. The method as set forth in claim 1, wherein the at least one electrode is a multipolar electrode and the application of the oscillating electric field is multipolar.

10. The method as set forth in claim 1, wherein said step of applying said oscillating electric field comprises the step of operating said electrical signal source with a pulse width of selected from the range of 50 to 500 microseconds.

11. The method as set forth in claim 1, wherein said step of applying said oscillating electric field comprises the step of operating said electrical signal source with a voltage selected from the range of 0.1 to 20 volts.