Method and apparatus for assessing cardiac functional status

• US 6,473,646 B2
• Filed: 04/18/2000
• Issued: 10/29/2002
• Est. Priority Date: 04/18/2000
• Status: Expired due to Term

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Sanders, Richard S., Kadhiresan, Veerichetty, KenKnight, Bruce H., Sun, Weimin
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US09/551,310
• Publication Number:
  US 20020120305A1
• Time in Patent Office: 924 Days
• Field of Search: 600/510, 600/508, 600/526, 600/587, 607/17, 607/18, 607/19, 607/27
• US Class Current: 607/27
• CPC Class Codes: A61N 1/36542 controlled by body motion, e.g. acceleration

Abstract

A method for assessing cardiac function suitable for incorporation into an implantable cardiac rhythm management device. By measuring daily exertion levels in accordance with the invention, an assessment of cardiac function can be made that has been found to correlate well with conventional clinical classifications. The invention also provides for assessing cardiac function in conjunction with different pacing schemes designed to treat heart failure and using the assessment to select the best such scheme for the patient.

Claims

1. A method for operating a cardiac management device, comprising:

measuring a moving average over a specified averaging period of exertion levels attained by a patient during daily activities;

extracting daily maximal exertion levels from the measured moving average exertion levels for a specified number of days;

classifying the patient'"'"'s cardiac functional status based upon the daily maximum daily exertion levels; and

,

performing a testing sequence in which different pacing schemes are tried for predetermined periods and a patient'"'"'s functional status is assessed for each scheme tried.

2. The method of claim 1 wherein the exertion levels are moving averaged over a time period of between approximately 30 seconds and 10 minutes.

3. The method of claim 1 wherein the exertion levels are measured by an implantable accelerometer.

4. The method of claim 1 wherein the exertion levels are measured by an implantable minute ventilation sensor.

5. The method of claim 1 wherein the steps are performed automatically at periodic times by an implantable device.

6. The method of claim 5 wherein the daily maximal exertion levels are registered and stored by the device.

7. The method of claim 6 further comprising transmitting the registered and stored daily maximal exertion levels to an external programmer for the device.

8. The method of claim 5 further comprising automatically selecting a drug therapy capable of being delivered by the device.

9. The method of claim 5 further comprising activating a selected diagnostic monitoring feature performed by the device when measured maximal exertion levels reach a selected threshold.

10. The method of claim 5 further comprising turning off or turning on device therapeutic features in accordance with measured maximal exertion levels.

11. The method of claim 5 further comprising:

performing a test sequence in which different therapies capable of being delivered by the device are tried while maximal exertion levels associated with the therapy are measured; and

,

automatically reconfiguring device parameter settings to select the optimum therapy for delivery by the device in accordance with the measured exertion levels.

12. The method of claim 11 wherein the device is a cardiac pacemaker and the different therapies are pacing schemes.

13. The method of claim 1 further comprising computing and storing averages of daily maximal exertion levels over a specified period of time.

14. The method of claim 1 further comprising automatically adjusting a pacing scheme of the device based upon the extracted maximal exertion levels.

15. A cardiac rhythm management device, comprising:

sensing channels for sensing atrial and ventricular depolarization signals, each channel including an electrode and a sense amplifier;

a pulse generator for delivering pacing pulses to the atrium and/or ventricle;

an exertion level sensor; and

,

a processor for controlling the delivery of pacing pulses in response to elapsed time intervals and detected depolarization signals in accordance with a programmed mode, wherein the processor is programmed to;

measure a moving average over a specified averaging period of exertion levels attained by the patient during daily activities;

extract daily maximal exertion levels from the measured moving average exertion levels for a specified number of days;

classify the patient'"'"'s cardiac functional status based upon the daily maximum daily exertion levels;

perform a testing sequence in which different pacing schemes are tried for predetermined periods and a patient'"'"'s functional status is assessed for each scheme tried.

16. The device of claim 15 wherein the processor is programmed to automatically adjust a pacing scheme of the device based upon the extracted maximal exertion levels.

17. The device of claim 16 wherein the processor is programmed to perform a testing sequence in which different pacing schemes are tried for predetermined periods and a patient'"'"'s functional status is assessed while each scheme is tried.

18. The device of claim 17 wherein the processor is programmed to insert a wash out period between trials of different pacing schemes.

19. The device of claim 17 wherein the processor is programmed to automatically select for use the pacing scheme resulting in the most improved functional status of a patient as determined by the testing sequence.

20. The device of claim 15 wherein the processor is programmed to activate a diagnostic monitoring operation when there is a change in the patient'"'"'s status as reflected by measured exertion levels.