DNA diagnostics based on mass spectrometry

  • US 6,500,621 B2
  • Filed: 02/28/2001
  • Issued: 12/31/2002
  • Est. Priority Date: 03/17/1995
  • Status: Expired due to Term
First Claim
Patent Images

1. A process for detecting one or more target nucleic acid sequences in a biological sample, comprising:

  • a) digesting nucleic acids from the sample;

    b) analyzing digested fragments by mass spectrometry;

    c) detecting a target nucleic acid sequence by a specific molecular weight, wherein detection of the target nucleic acid by mass spectrometry indicates the presence of the target nucleic acid sequence in the biological sample.

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