Pharmaceutical composition comprising entacapone, levodopa, and carbidopa

  • US 6,500,867 B1
  • Filed: 06/29/2000
  • Issued: 12/31/2002
  • Est. Priority Date: 06/30/1999
  • Status: Expired due to Term
First Claim
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1. An oral solid tablet composition comprising pharmacologically effective amounts of entacapone, levodopa and carbidopa, or pharmaceutically acceptable salts or hydrates thereof, and a pharmaceutically acceptable excipient, wherein a substantial portion of carbidopa or a pharmaceutically acceptable salt or hydrate thereof is separated from entacapone and levodopa or pharmaceutically acceptable salts or hydrates thereof in the tablet.

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