Non-invasive focused energy blood withdrawal and analysis system

• US 6,503,209 B2
• Filed: 05/18/2001
• Issued: 01/07/2003
• Est. Priority Date: 05/18/2001
• Status: Expired due to Fees

• Current Assignee: A-Hamid Hakki, Said I. Hakky
• Original Assignee: A-Hamid Hakki, Said I. Hakky
• Inventors: Hakki, A-Hamid, Hakky, Said I.
• Primary Examiner(s): BRINSON, PATRICK F
• Application Number:
  US09/859,592
• Publication Number:
  US 20020173732A1
• Time in Patent Office: 599 Days
• Field of Search: 600/573-578, 606/2, 606/9, 606/10, 606/13, 606/16
• US Class Current: 600/573
• CPC Class Codes: A61B 2017/00765 Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150099 by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/15134 Bladeless capillary blood sampling devices, i.e. devices for perforating the skin in order to obtain a blood sample but not using a blade, needle, canula, or lancet, e.g. by laser perforation, suction or pressurized fluids
• CPC Class Codes: A61B 5/15136 by use of radiation, e.g. laser
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood

Abstract

A non-invasive focused energy blood withdrawal and analysis system (1) is provided. A laser energy source (11) and a vacuum pump (9) are mounted within a portable housing. A focused laser beam is directed on an epidermal layer to create a microscopic incision in the epidermis of a patient. Vacuum pump (9) draws a blood sample from the microscopic incision through a disposable fluid displacement device (2). A removable dry slide is placed in the fluid path of the blood sample to receive the blood sample. Further, sensor elements (6 and 7) are mounted within the portable housing on either side of the removable dry slide (8) to perform blood analysis. A logic processing unit (5) is provided in electrical communication with sensor elements (6 and 7) for performing the necessary blood analysis.

Claims

1. A non-invasive focused energy blood withdrawal and analysis system comprising:

a housing;

an energy source mounted within said housing for generating an energy beam, said energy beam being focused on an epidermal layer to create a microscopic opening in said epidermal layer;

a logic processing unit electrically coupled with said energy source for controlling said energy source;

a vacuum pump mounted within said housing;

a suction tube having a first end in fluid communication with said vacuum pump and a second end placed over said microscopic opening to draw a blood sample in a fluid path within said suction tube;

a slide located in said fluid path of said blood sample and removably mounted within said housing for collecting said blood sample; and

,

at least one sensor in electrical communication with said logic processing unit for analyzing said blood sample collected on said slide.

2. The non-invasive focused energy blood withdrawal system as recited in claim 1 wherein said energy source is a laser.

3. The non-invasive focused energy blood withdrawal system as recited in claim 1 wherein said energy source is a sonic wave generator.

4. The non-invasive focused energy blood withdrawal system as recited in claim 1 wherein said energy source is an electrical power source.

5. The non-invasive focused energy blood withdrawal system as recited in claim 1 wherein said slide has a reagent layer formed thereon.

6. The non-invasive focused energy blood withdrawal system as recited in claim 1 wherein said vacuum pump has a variable power output.

7. The non-invasive focused energy blood withdrawal system as recited in claim 1 wherein said energy beam is pulsed at a controllable pulse rate.

8. The non-invasive focused energy blood withdrawal system as recited in claim 1 wherein said housing has a display mounted thereon, said display being in electrical communication with said logic processing unit.

9. The non-invasive focused energy blood withdrawal system as recited in claim 1 wherein said energy source has a variable power output.

10. The non-invasive focused energy blood withdrawal system as recited in claim 1 wherein said energy beam has a variable frequency.

11. A non-invasive focused energy blood withdrawal and analysis system comprising:

a hand-held housing;

an energy source mounted within said housing for generating an energy beam, said energy beam being focused on an epidermal layer to create a microscopic opening in said epidermal layer;

a logic processing unit electrically coupled with said energy source for controlling said energy source;

a vacuum pump mounted within said housing;

a suction tube removably mounted within said hand-held housing, said suction tube having a first end in fluid communication with said vacuum pump and a second end placed over said microscopic opening to draw a blood sample in a fluid path within said suction tube;

a slide located in said fluid path of said blood sample and removably mounted within said housing for collecting said blood sample;

a sealing member removably fixed to the base of said hand-held housing for contacting said epidermal layer; and

,

at least one sensor in electrical communication with said logic processing unit for analyzing said blood sample collected on said slide.

12. The non-invasive focused energy blood withdrawal system as recited in claim 11 wherein said energy source is a laser.

13. The non-invasive focused energy blood withdrawal system as recited in claim 11 wherein said energy source is a sonic wave generator.

14. The non-invasive focused energy blood withdrawal system as recited in claim 11 wherein said energy source is an electrical power source.

15. The non-invasive focused energy blood withdrawal system as recited in claim 11 wherein said slide has a reagent layer formed thereon.

16. The non-invasive focused energy blood withdrawal system as recited in claim 11 wherein said vacuum pump has a variable power output.

17. The non-invasive focused energy blood withdrawal system as recited in claim 11 wherein said energy beam is pulsed at a controllable pulse rate.

18. The non-invasive focused energy blood withdrawal system as recited in claim 11 wherein said hand-held housing has a display mounted thereon, said display being in electrical communication with said logic processing unit.

19. The non-invasive focused energy blood withdrawal system as recited in claim 11 wherein said energy source has a variable power output.

20. The non-invasive focused energy blood withdrawal system as recited in claim 11 wherein said energy beam has a variable frequency.