Triazolo(4,5-d)pyrimidine compounds

  • US 6,525,060 B1
  • Filed: 03/08/2000
  • Issued: 02/25/2003
  • Est. Priority Date: 12/04/1998
  • Status: Expired
First Claim
Patent Images

1. A compound of formula (I) embedded imagewherein:

  • R1 is C3-5 alkyl optionally substituted by one or more halogen atoms;

    R2 is a phenyl group, optionally substituted by one or more fluorine atoms;

    R3 and R4 are both hydroxy;

    R is XOH, where X is CH2, OCH2CH2 or a bond;

    or a pharmaceutically acceptable salt or solvate thereof, or a solvate of such a salt provided that;

    when X is CH2 or a bond, R1 is not propyl;

    when X is CH2 and R1 is CH2CH2CF3, butyl or pentyl, the phenyl group at R2 must be substituted by fluorine;

    when X is OCH2CH2 and R1 is propyl, the phenyl group at R2 must be substituted by fluorine.

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