Ultra-stable composition comprising moringa oil and it's derivatives and uses thereof

• US 6,528,075 B1
• Filed: 07/27/2001
• Issued: 03/04/2003
• Est. Priority Date: 07/27/2001
• Status: Expired due to Term

• Current Assignee: International Flora Technologies Limited
• Original Assignee: International Flora Technologies Limited
• Inventors: Brown, James H., Kleiman, Robert
• Primary Examiner(s): Page, Thurman K.
• Assistant Examiner(s): Sheikh, Humera N.
• Application Number:
  US09/917,091
• Time in Patent Office: 585 Days
• Field of Search: 424/401, 424/776, 514/844, 514/847
• US Class Current: 424/401
• CPC Class Codes: A61K 2800/522 Antioxidants; Radical scavengers
• CPC Class Codes: A61K 8/23 Sulfur; Selenium; Tellurium; Compounds thereof
• CPC Class Codes: A61K 8/365 Hydroxycarboxylic acids; Ketocarboxylic acids
• CPC Class Codes: A61K 8/4973 with oxygen as the only hetero atom
• CPC Class Codes: A61K 8/498 having 6-membered rings or their condensed derivatives, e.g. coumarin
• CPC Class Codes: A61K 8/66 Enzymes
• CPC Class Codes: A61K 8/676 Ascorbic acid, i.e. vitamin C
• CPC Class Codes: A61K 8/678 Tocopherol, i.e. vitamin E
• CPC Class Codes: A61K 8/922 of vegetable origin
• CPC Class Codes: A61Q 1/02 Preparations containing skin colorants, e.g. pigments preparations in powder form A61Q1/12
• CPC Class Codes: A61Q 1/06 Lipsticks
• CPC Class Codes: A61Q 17/00 Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
• CPC Class Codes: A61Q 17/04 Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/08 Anti-ageing preparations

Abstract

A composition is described that comprises moringa oils, or its derivatives, produced from the moringa plant in combination with an oxidation stabilizing system comprising at least one tocopherol. The oils derived from the moringa plant should have a percent methylene interrupted unsaturation of less than 1%. The composition may have at least one supplemental additive, such as malic acid, kojic acid, or ascorbic acid, present in an amount of from 0.01 to 2% or more by weight of the composition and the tocopherol is present in an amount of from 0.01 to 5% by weight of the composition.

Claims

1. A composition comprising

a. a long-chain oil of moringa, said long-chain oil has a methylene interrupted unsaturation of less than 10%, in combination with

b. at least one tocopherol, wherein said tocopherol is present in an amount of from 0.01 to 5% by weight of said long-chain oil, wherein said tocopherol provides an oxidation stability to the long-chain oil of more than 200% relative to the oxidation stability of the oil alone.

2. A composition comprising

a. a long-chain oil of moringa, said long-chain oil has a percent methylene interrupted unsaturation of less than 5%, in combination with

b. at least one tocopherol, wherein said tocopherol provides an oxidation stability to the long-chain oil of more than 200% relative to the oxidation stability of the oil alone.

3. A composition comprising

a. a long-chain oil of moringa, and said long-chain oil has a methylene interrupted unsaturation of less than 1%, in combination with

b. at least one tocopherol, wherein said tocopherol provides an oxidation stability to the long-chain oil of more than 200% relative to the oxidation stability of the oil alone.

4. A composition comprising Moringa nut oil having a methylene interrupted unsaturation of less than 10% in combination with at least one tocopherol wherein said tocopherol provides an oxidation stability to the Moringa nut oil of more than 200% relative to the Moringa nut oil alone.

5. A composition comprising

a. a long-chain oil of moringa, said long-chain oil has a methylene interrupted unsaturation of less than 10%, in combination with

b. at least one tocopherol and at least one supplemental additive selected from the group consisting of kojic acid, malic acid, and ascorbic acid, wherein said tocopherol is present in an amount of from 0.01 to 5% by weight of said long-chain oil, wherein said tocopherol and said at least one supplemental additive in combination provide an oxidation stability to the long-chain oil of more than 200% relative to the oxidation stability of the oil alone.

6. A composition comprising

a. a long-chain oil of moringa, said long-chain oil has a methylene interrupted unsaturation of less than 5%, in combination with

b. at least one tocopherol and at least one supplemental additive selected from the group consisting of kojic acid, malic acid, and ascorbic acid, wherein said tocopherol and said at least one supplemental additive in combination provide an oxidation stability to the long-chain oil of more than 200% relative to the oxidation stability of the oil alone.

7. A composition comprising

a. a long-chain oil of moringa, and said long-chain oil has a methylene interrupted unsaturation of less than 1%, in combination with

b. at least one tocopherol and at least one supplemental additive selected from the group consisting of kojic acid, malic acid, and ascorbic acid, wherein said tocopherol and said at least one supplemental additive in combination provide an oxidation stability to the long-chain oil of more than 200% relative to the oxidation stability of the oil alone.

8. A composition comprising

a. Moringa nut oil having a methylene interrupted unsaturation of less than 10% in combination with

b. at least one tocopherol and at least one supplemental additive selected from the group consisting of kojic acid, malic acid, and ascorbic acid,

c. wherein said tocopherol and said at least one supplemental additive in combination provide an oxidation stability to the Moringa nut oil of more than 200% relative to the Moringa nut oil alone.

9. The emollient composition of claim 8 wherein said supplement additive comprises kojic acid.

10. The emollient composition of claim 8 wherein said at least one supplemental additive is present in an amount of from 0.01 to 2% by weight of said Moringa nut oil and said tocopherol is present in an amount of from 0.01 to 5% by weight of said macadamia nut oil.

11. The emollient composition of claim 10 wherein said Moringa nut oil has a percent methylene interrupted unsaturation of less than 1%.

12. A composition comprising

a. a long-chain ethyl ester of moringa oil, said long-chain ethyl ester has a methylene interrupted unsaturation of less than 10%, in combination with

b. at least one tocopherol, wherein said tocopherol is present in an amount of from 0.01 to 5% by weight of said long-chain ethyl ester, wherein said tocopherol provides an oxidation stability to the long-chain ethyl ester greater than 460% relative to the oxidation stability of the ethyl ester alone.

13. A composition comprising

a. a long-chain ethyl ester of moringa oil, said long-chain ethyl ester has a methylene interrupted unsaturation of less than 5%, in combination with

b. at least one tocopherol, wherein said tocopherol provides an oxidation stability to the long-chain ethyl ester greater than 460% relative to the oxidation stability of the ethyl ester alone.

14. A composition comprising

a. a long-chain ethyl ester of moringa oil, and said long-chain ethyl ester has a methylene interrupted unsaturation of less than 1%, in combination with

b. at least one tocopherol, wherein said tocopherol provides an oxidation stability to the long-chain ethyl ester greater than 460% relative to the oxidation stability of the ethyl ester alone.

15. A composition comprising Moringa nut oil ethyl ester having a methylene interrupted unsaturation of less than 10% in combination with at least one tocopherol wherein said tocopherol provides an oxidation stability to the Moringa nut oil ethyl ester greater than 460% relative to the Moringa nut oil ethyl ester alone.

20. The emollient composition of claim 15 wherein said supplement additive comprises kojic acid.

21. The emollient composition of claim 15 wherein said at least one supplemental additive is present in an amount of from 0.01 to 2% by weight of said Moringa nut oil ethyl ester and said tocopherol is present in an amount of from 0.01 to 5% by weight of said macadamia nut oil ethyl ester.

16. A composition comprising

a. a long-chain ethyl ester of moringa oil, said long-chain ethyl ester has a methylene interrupted unsaturation of less than 10%, in combination with

b. at least one tocopherol and at least one supplemental additive selected from the group consisting of kojic acid, malic acid, and ascorbic acid, wherein said tocopherol is present in an amount of from 0.01 to 5% by weight of said long-chain ethyl ester, wherein said tocopherol and said at least one supplemental additive in combination provide an oxidation stability to the long-chain ethyl ester greater than 460% relative to the oxidation stability of the ethyl ester alone.

17. A composition comprising

a. a long-chain ethyl ester of moringa oil, said long-chain ethyl ester has a methylene interrupted unsaturation of less than 5%, in combination with

b. at least one tocopherol and at least one supplemental additive selected from the group consisting of kojic acid, malic acid, and ascorbic acid, wherein said tocopherol and said at least one supplemental additive in combination provide an oxidation stability to the long-chain ethyl ester greater than 460% relative to the oxidation stability of the ethyl ester alone.

22. The emollient composition of claim 17 wherein said Moringa nut oil ethyl ester has a percent methylene interrupted unsaturation of less than 10%.

18. A composition comprising

a. a long-chain ethyl ester of moringa oil, and said long-chain ethyl ester has a percent methylene interrupted unsaturation of less than 1%, in combination with

b. at least one tocopherol and at least one supplemental additive selected from the group consisting of kojic acid, malic acid, and ascorbic acid, wherein said tocopherol and said at least one supplemental additive in combination provide an oxidation stability to the long-chain ethyl ester greater than 460% relative to the oxidation stability of the ethyl ester alone.

19. A composition comprising

a. Moringa nut oil ethyl ester having a percent methylene interrupted unsaturation of less than 20% in combination with

b. at least one tocopherol and at least one supplemental additive selected from the group consisting of kojic acid, malic acid, and ascorbic acid,

c. wherein said tocopherol and said at least one supplemental additive in combination provide an oxidation stability to the Moringa nut oil ethyl ester greater than 460% relative to the Moringa nut oil ethyl ester alone.