Spectrophotometer for tissue examination
First Claim
1. A method of transcranial examination of brain activity by measuring changes in electromagnetic radiation scattered and absorbed in a migration path in the brain comprising(a) introducing electromagnetic radiation of a selected wavelength into the brain at an input port placed at a selected location on the exterior of the head, (b) detecting, at a detection port placed at a selected location on the exterior of the head, radiation of said selected wavelength that has migrated in the brain, (c) causing stimulation of a brain activity while introducing said radiation at said input port and while detecting radiation of said detection port, (d) processing signals of said detected radiation that has migrated in the brain to create processed data, and (e) determining a characteristic of said brain activity by correlating said processed data with said caused stimulation of said brain activity.
1 Assignment
0 Petitions
Accused Products
Abstract
A method and apparatus for transcranial examination of brain activity. Electromagnetic radiation of a selected wavelength is introduced into the brain from an input port located on an exterior of the subject'"'"'s head. Radiation that has migrated through the subject'"'"'s head is detected at a detection port to generate detected signals. While introducing and detecting the electromagnetic radiation, stimulation of brain activity is induced. The detected radiation signals are processed, and the processed signals are analyzed to determine a characteristic of the brain activity by correlating the processed signals with the stimulation.
289 Citations
37 Claims
-
1. A method of transcranial examination of brain activity by measuring changes in electromagnetic radiation scattered and absorbed in a migration path in the brain comprising
(a) introducing electromagnetic radiation of a selected wavelength into the brain at an input port placed at a selected location on the exterior of the head, (b) detecting, at a detection port placed at a selected location on the exterior of the head, radiation of said selected wavelength that has migrated in the brain, (c) causing stimulation of a brain activity while introducing said radiation at said input port and while detecting radiation of said detection port, (d) processing signals of said detected radiation that has migrated in the brain to create processed data, and (e) determining a characteristic of said brain activity by correlating said processed data with said caused stimulation of said brain activity.
-
8. A method of transcranial examination of brain activity by measuring changes in electromagnetic radiation scattered and absorbed in a migration path in the brain comprising
(a) introducing electromagnetic radiation of a selected wavelength into the brain simultaneously at a first input port and at a second input port, said first input port and said second input port being placed at a first selected location and a second selected location on the exterior of the head, respectively, (b) detecting simultaneously, at a first detection port placed at a selected location on the exterior of the head, radiation that has migrated in the brain from said first input port to said first detection port and, at a second detection port placed at second selected location on the exterior of the head, radiation that has migrated in the brain from said second input port to said second detection port, (c) causing stimulation of a brain activity while introducing said radiation at said first and second input ports and while detecting radiation at said first and second detection ports, (d) processing signals of said detected radiation that has migrated in the brain to create processed data, and (e) determining a characteristic of said brain activity by correlating said processed data to said caused stimulation of said brain activity.
-
19. A cognition spectrophotometer system for transcranial examination of brain activity by measuring changes in electromagnetic radiation scattered and absorbed in a migration path in the brain comprising
(a) a light source adapted to introduce electromagnetic radiation of a selected wavelength into the brain at an input port placed at a selected location on the exterior of the head, (b) a detector adapted to detect, at a detection port placed at a selected location on the exterior of the head, radiation of said selected wavelength that has migrated in the brain, (c) stimulation means adapted to cause stimulation of a brain activity while introducing said selected wavelength and while detecting radiation at said detection port, (d) processing means adapted to process signals of said detected radiation that has migrated in the brain to create processed data, and (e) evaluation means adapted to determine a characteristic of said brain activity by correlating said processed data with said caused stimulation of said brain activity.
-
26. A cognition spectrophotometer system for transcranial examination of brain activity by measuring changes in electromagnetic radiation scattered and absorbed in a migration path in the brain comprising
(a) a first light source and a second light source adapted to introduce electromagnetic radiation of a selected wavelength into the brain simultaneously at a first input port and at a second input port, said first input port and said second input port being placed at a first selected location and a second selected location on the exterior of the head, respectively, (b) a first detector and a second detector adapted to detect simultaneously, at a first detection port placed at a selected location on the exterior of the head, radiation that has migrated in the brain from said first input port to said first detection port and, at a second detection port placed at second selected location on the exterior of the head, radiation that has migrated in the brain from said second input port to said second detection port, (c) stimulation means adapted to cause stimulation of a brain activity while introducing said radiation at said first and second input ports and while detecting radiation at said first and second detection ports, (d) processing means adapted to process signals of said detected radiation that has migrated in the brain to create processed data, and (e) evaluation means adapted to determine a characteristic of said brian activity by correlating said processed data to said caused stimulation of said brain activity.
Specification