Synthetic biomaterial compound of calcium phosphate phases particularly adapted for supporting bone cell activity

  • US 6,585,992 B2
  • Filed: 10/04/2001
  • Issued: 07/01/2003
  • Est. Priority Date: 09/01/1995
  • Status: Expired due to Term
First Claim
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1. A method for substituting natural bone at sites of skeletal surgery in human and animal hosts with a biomaterial compound comprising calcium, oxygen and phosphorous, wherein a portion of at least one of said elements is substituted with an element having an ionic radius of approximately 0.1 to 0.6 Å

  • ;

    said method comprising the steps of;

    implanting said biomaterial compound at the site of skeletal surgery wherein such implantation promotes the formation of new bone tissue at the interfaces between said biomaterial compound and said host, the progressive removal of said biomaterial compound primarily through osteoclast activity, and the replacement of that portion of said biomaterial compound removed by further formation of new bone tissue by osteoblast activity, such progressive removal and replacement being inherent in the natural bone remodeling process.

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