System for monitoring and controlling pressure and concentration values in a fluid conduit

• US 6,609,071 B2
• Filed: 12/06/2000
• Issued: 08/19/2003
• Est. Priority Date: 12/06/2000
• Status: Expired due to Fees

• Current Assignee: Project Cd
• Original Assignee: Project Cd
• Inventors: Warhurst, Julian, Shapiro, Philip, Davis-Reinhold, John, Hayes, Charles Daniel
• Primary Examiner(s): Barlow, John
• Assistant Examiner(s): Cherry, Stephen J.
• Application Number:
  US09/729,703
• Publication Number:
  US 20020069023A1
• Time in Patent Office: 986 Days
• Field of Search: 604/30, 604/31, 604/508, 604/65, 604/67, 604/151, 702/50, 702/53
• US Class Current: 702/50
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61M 2205/3355 Controlling downstream pump pressure
• CPC Class Codes: A61M 5/007 for contrast media
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: G01N 27/10 Investigation or analysis specially adapted for controlling or monitoring operations or for signalling

Abstract

A system for monitoring and regulating pressure and concentration in a moving fluid stream inside of a conduit is provided. The fluid stream includes a first fluid. The system comprises an infusion assembly that includes a catheter having a series of holes distributed around an exterior surface and a pumping system for introducing a second fluid into said catheter to create a solution mixture. A data collection system is provided for collecting data indicative of pressure and conductivity values. Data from the data collection system is forwarded to a data processing and control apparatus. The data processing and control apparatus comprises conversion means for converting the measured conductivity into a concentration value and control means for controlling operation of the infusion assembly based on a comparison of selected values with data received from the data collection system. A user control and analysis system allows user interaction. The system allows complete automatic control over the fluid distribution within a fluid conduit in response to measured values.

Claims

1. A system for monitoring and regulating pressure in a moving fluid stream inside of a conduit, the system comprising:

an infusion assembly including,

a catheter having a series of holes distributed around an exterior surface,

injection means for introducing a fluid into the catheter, and

a pump for delivering fluid to the injection means;

a data collection system including,

a first pressure transducer attached to a pressure chamber of the pump, and

a second pressure transducer attached to an end of the catheter for measuring the pressure in a pressure chamber line of the catheter;

a data processing and control system for processing data collected from the second pressure transducer attached to the end of the catheter and for controlling operations of the infusion assembly based on a comparison of a plurality of selected values and data received from the data collection system; and

a user control and analysis system for allowing user interaction.

2. The system of claim 1, wherein the infusion assembly comprises a stepper motor and a stepper motor controller for powering the pump.

3. The system of claim 1, wherein the injection means comprises a syringe and wherein a solenoid valve controls pumping from the syringe to the catheter.

4. The system of claim 3, comprising a pumping electronic switch for providing a signal when the syringe is full and a refill electronic switch for providing a signal when the syringe is empty.

5. The system of claim 1, further comprising a pressure switch for setting a desired pumping pressure.

6. The system of claim 1, wherein the first pressure transducer is transducer in a wall of the conduit and the second pressure transducer is a piezo-resistive pressure transducer at a proximal end of the catheter.

7. The system of claim 1, wherein the data processing and control system comprises a pressure meter for outputting signals to the infusion assembly.

8. The system of claim 7, further comprising a pressure monitoring system including an amplifier, an A/D converter, and a CPU.

9. The system of claim 7, wherein the pressure meter comprises means for controlling infusion based on a plurality of pressure parameters including a pulse width and a dead time.

10. The system of claim 1, wherein the user control and analysis system allows the user to select one or more desired values and parameters.

11. A system for monitoring and regulating pressure and concentration in a moving fluid stream inside of a conduit, wherein the fluid stream includes a first fluid, the system comprising:

an infusion assembly including,

a catheter having a series of holes distributed around an exterior surface,

injection means for introducing a second fluid into the catheter to create a solution mixture, and

a pump for delivering the second fluid to the injection means;

a data collection system including,

a first pressure transducer attached to a pressure chamber of the pump,

a second pressure transducer attached to an end of the catheter, and

a sensor means within the conduit for measuring a conductivity of the solution mixture;

data processing and control apparatus including conversion means for converting the measured conductivity into a concentration value, and control means for controlling operation of the infusion assembly based on a comparison of a plurality of selected values with data received from the data collection system; and

a user control and analysis system for allowing user interaction.

12. The system of claim 11, wherein the sensor means within the conduit comprises a probe having a plurality of real electrodes.

13. The system of claim 12, wherein the probe comprises nineteen real electrodes.

14. The system of claim 12, wherein a primary virtual electrode is disposed at a midpoint between any two of the real electrodes.

15. The system of claim 14, wherein the real electrodes and the primary virtual electrodes are capable of being connected to form ninety-six equilateral triangles for analysis of conductivity in a plurality of specified regions inside of the conduit.

16. The system of claim 11, wherein the data processing and control system calculates conductivity in a specified region of the conduit by calculating the conductivity in a region between two electrodes.

17. The system of claim 11, further comprising means for prompting conductivity measurements during an initial period of flow of the second fluid through the catheter, the initial period being between 10 and 18 μ

s.

18. The system of claim 11, wherein the data processing and control apparatus comprises a conductivity meter including an amplifier, an A/D converter, and a CPU for processing conductivity measurements taken by the data collection system.

19. The system of claim 18, wherein the A/D converter comprises a microprocessor chip programmed using a hexadecimal assembly programming language.

20. The system of claim 11, wherein the user control and analysis system comprises one or more pull down menus for the user to select one or more viewing options.

21. The system of claim 11, wherein the user control and analysis system allows the user to select one or more of a plurality of specific measurement regions by selecting one or more electrode pairs.

22. The system of claim 11, wherein the control means allows a user to select a pressure threshold.

23. The system of claim 11, wherein the control means allows the user to select to replay a pre-recorded test data.

24. The system of claim 11, wherein the infusion assembly comprises a stepper motor and a stepper motor controller for powering the pump.

25. The system of claim 11, wherein the injection means comprises a syringe and wherein a solenoid valve controls pumping from the syringe to the catheter.

26. The system of claim 25, further comprising a pumping electronic switch for providing a signal when the syringe is full and a refill electronic switch for providing a signal when the syringe is empty.

27. The system of claim 11, further comprising a pressure switch for setting a desired pumping pressure.

28. The system of claim 11, wherein the first pressure transducer is transducer in a wall of the conduit and the second pressure transducer is a piezo-resistive pressure transducer at a proximal end of the catheter.

29. The system of claim 11, wherein the data processing and control system comprises a pressure meter for outputting signals to the infusion assembly.

30. The system of claim 29, further comprising a pressure monitoring system that includes an amplifier, an A/D converter, and a CPU.

31. The system of claim 29, wherein the pressure meter comprises means for controlling infusion based on a plurality of pressure parameters including a pulse width and a dead time.