Bone-treatment instrument and method

• US 6,622,731 B2
• Filed: 01/11/2002
• Issued: 09/23/2003
• Est. Priority Date: 01/11/2001
• Status: Expired due to Fees

• Current Assignee: AngioDynamics, Inc.
• Original Assignee: Rita Medical Systems Incorporated (AngioDynamics, Inc.)
• Inventors: Daniel, Steven A., Jimbo, Takehito, Pearson, Robert, Frischmeyer, Karen, Russell, Robert D., Tamayo, Andres, Balbierz, Daniel J.
• Primary Examiner(s): PEFFLEY, MICHAEL F
• Application Number:
  US10/044,081
• Publication Number:
  US 20020133148A1
• Time in Patent Office: 620 Days
• Field of Search: 606/27-31, 606/41, 606/213-215, 128/898
• US Class Current: 128/898
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 2017/003 Steerable
• CPC Class Codes: A61B 2018/00029 open
• CPC Class Codes: A61B 2018/00083 low, i.e. electrically insulating
• CPC Class Codes: A61B 2018/00142 lubricating
• CPC Class Codes: A61B 2018/00654 with individual control of each of a plurality of energy emitting elements
• CPC Class Codes: A61B 2018/00755 Resistance or impedance
• CPC Class Codes: A61B 2018/00797 measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/00875 Resistance or impedance
• CPC Class Codes: A61B 2018/1435 Spiral
• CPC Class Codes: A61B 2090/3925 ultrasonic
• CPC Class Codes: A61B 2218/002 Irrigation
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps

Abstract

Ablation devices and associated methods are provided for use in palliative treatment of a bone tumor on or in a compact bone region. The bone treatment devices include an elongate probe having a distal end. A proximal end of the probe supports placement in a location at or adjacent to the bone tumor. Electrodes are carried within the probe for deployment from the distal end into the bone tumor. The electrodes may be shapable to create, upon deployment, an array of electrodes that defines a geometric area within the bone tumor. Application of energy, for example energy from a radio frequency (RF) source, to the area of the bone tumor via the electrodes destroys at least a portion of the nerve receptors located in or adjacent to the tumor and produces a reduction in pain associated with the bone tumor. Liquid, such as a polymer in liquid form, may be injected through an electrode needle, with electrode heating being employed to allow introduction of the polymer solution through the needle and/or hardening at the site of injection.

Claims

1. A method of injecting into an internal body site in a subject, a thermoset or thermoplastic polymer material, comprising

positioning against or adjacent the internal body site, the distal end of an instrument having a distal-end electrode needle which can be activated to produce localized heating,

with said tip inserted into or against body site, activating said needle under conditions effective to raise the temperature of said site, in the region of the needle,

injecting a thermoset or thermoplastic polymer liquid into the site, before, during or following said activating step, such that the needle and surrounding body site is at a temperature that allows introduction of the polymer solution through the needle and hardening at the site of injection.

2. The method of claim 1, for use in palliatively treating a pain-causing bone tumor, wherein said needle is positioned within the tumor, said activating step is effective to ablate tumor tissue by heating, and said polymer liquid when it thermoset or thermoplastics, is effective to stabilize movement the ablated tumor region.

3. The method of claim 2, wherein said polymer liquid is a polymethylmethacrylate, said injecting includes injecting the liquid through an electrode needle, and said activating is effective to maintain the temperature of the polymer liquid above its glass transition temperature while the liquid is being injected through the needle.