Accelerometer-based heart sound detection for autocapture

• US 6,650,940 B1
• Filed: 02/02/2000
• Issued: 11/18/2003
• Est. Priority Date: 02/02/2000
• Status: Expired due to Term

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Spinelli, Julio C., Carlson, Gerrard M., Zhu, Qingsheng
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US09/496,832
• Time in Patent Office: 1,385 Days
• Field of Search: 607/28, 607/19, 607/27, 600/528
• US Class Current: 607/28
• CPC Class Codes: A61N 1/36542 controlled by body motion, e.g. acceleration
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold

Abstract

An implantable cardiac rhythm management device capable of automatically detecting intrinsic and evoked response of a patient'"'"'s heart. The device operates in an automatic capture verification mode, wherein a global accelerometer signal is utilized to identify heart sounds (S₁ and S₂) of the patient'"'"'s heart. The presence or absence of one or more of the heart sounds S₁ and S₂ in the accelerometer signal indicates whether a stimulation pulse evokes a response by the patient'"'"'s heart. The device may automatically adjust the stimulation output in accordance with a step down stimulation protocol, wherein the presence of a predetermined heart sound indicates capture. Also, the device may suspend the automatic capture verification sequence if the patient'"'"'s physical activity level exceeds a predetermined threshold.

Claims

1. A cardiac rhythm management device capable of functioning in a preset stimulation and/or autocapture mode having preset stimulation rates and timing intervals, said rhythm management device comprising:

a pulse generator that generates a stimulation pulse for delivery to at least one of an atrium and a ventricle of a heart;

an accelerometer that transmits a signal associated with accelerations of the heart;

a controller electrically coupled to said pulse generator and said accelerometer, said controller identifying heart sounds from the signal of the accelerometer over corresponding cardiac cycles and further determining whether an identified heart sound is associated with delivery of the stimulation pulse to the heart;

wherein said controller includes a detection window having a predefined duration;

wherein said controller determines a maximum output of said signal of the accelerometer for at least one cardiac cycle; and

wherein a center of the detection window is aligned with a determined maximum output of said signal of the accelerometer during a first cardiac cycle.

2. A cardiac rhythm management device according to claim 1, wherein said accelerometer is electrically coupled to a band pass filter having a range of between 20-70 Hertz for filtering the signal associated with accelerations of the heart.

3. A cardiac rhythm management device according to claim 1, wherein said means for determining whether an identified heart sound is associated with delivery of the stimulation pulse to the heart includes a step down stimulation protocol.

4. A cardiac rhythm management device according to claim 1, wherein the identified heart sound is associated with at least one of S₁ and S₂.

5. A cardiac rhythm management device according to claim 1, wherein the identified heart sound is associated with S₁.

6. A cardiac rhythm management device according to claim 1, wherein the identified heart sound is associated with S₂.

7. A cardiac rhythm management device capable of functioning in a preset stimulation and/or autocapture mode having preset stimulation rates and timing intervals, said rhythm management device comprising:

a pulse generator that generates a stimulation pulse for delivery to at least one of an atrium and a ventricle of a heart;

an accelerometer that transmits a signal associated with accelerations of the heart;

a controller electrically coupled to said pulse generator and said accelerometer, said controller identifying heart sounds from the signal of the accelerometer over corresponding cardiac cycles and further determining whether an identified heart sound is associated with delivery of the stimulation pulse to the heart; and

wherein said controller determines a patient activity level and terminates the determination as to whether the identified heart sound is associated with delivery of the stimulation pulse to the heart when the patient activity level exceeds a predetermined amount.

8. A cardiac rhythm management device according to claim 7, wherein the patient activity level is determined from the signal of the accelerometer.

9. A cardiac rhythm management device capable of functioning in a preset stimulation and/or autocapture mode having preset stimulation rates and timing intervals, said rhythm management device comprising:

generating means for generating a stimulation pulse for delivery to at least one of an atrium and a ventricle of a heart;

means for detecting and transmitting a signal associated with accelerations of the heart;

control means electrically coupled to said generating means and means for detecting, said control means for identifying heart sounds from the signal of the means for detecting occurring during a predefined period and corresponding to a cardiac cycle, and wherein said control means determines whether an identified heart sound is associated with delivery of the stimulation pulse to the heart;

wherein said control means determines a maximum output of the signal of the means for detecting for at least one cardiac cycle; and

wherein a midpoint of the predefined period is set to correspond with a timing of detection of a determined maximum output of the signal of the means for detecting during a first cardiac cycle.

10. A cardiac rhythm management device according to claim 9, wherein said means for detecting is electrically coupled to a band pass filter having a range of between 20-70 Hertz for filtering the signal associated with fluid and myocardial accelerations of the heart.

11. A cardiac rhythm management device according to claim 9, wherein said control means includes a step down stimulation protocol.

12. A cardiac rhythm management device according to claim 9, wherein the identified heart sound is associated with at least one of S₁ and S₂.

13. A cardiac rhythm management device according to claim 9, wherein the identified heart sound is associated with S₁.

14. A cardiac rhythm management device according to claim 9, wherein the identified heart sound is associated with S₂.

15. A cardiac rhythm management device capable of functioning in a preset stimulation and/or autocapture mode having preset stimulation rates and timing intervals, said rhythm management device comprising:

generating means for generating a stimulation pulse for delivery to at least one of an atrium and a ventricle of a heart;

means for detecting and transmitting a signal associated with accelerations of the heart;

control means electrically coupled to said generating means and means for detecting, said control means for identifying heart sounds from the signal of the means for detecting occurring during a predefined period and corresponding to a cardiac cycle, and wherein said control means determines whether an identified heart sound is associated with delivery of the stimulation pulse to the heart; and

wherein said control means determines a patient activity level and terminates the determination whether the identified heart sound is associated with delivery of the stimulation pulse to the heart when the patient activity level exceeds a predetermined amount.

16. A cardiac rhythm management device according to claim 15, wherein the patient activity level is determined from the signal of the means for detecting.

17. A method of determining whether a stimulation output is sufficient to evoke a response in a patient'"'"'s heart, said method comprising the steps of:

positioning an accelerometer adjacent a patient'"'"'s heart;

delivering a stimulation pulse having a predetermined output to a patient'"'"'s heart;

obtaining from the accelerometer a signal associated with fluid and myocardial accelerations of the heart;

identifying heart sounds from the signal of the accelerometer over a cardiac cycle corresponding with the stimulation pulse;

determining whether the identified heart sounds are associated with delivery of the stimulation pulse to the heart; and

determining a patient activity level and terminating the determination of whether the identified heart sound is associated with delivery of the stimulation pulse to the heart when the patient activity level exceeds a predetermined amount.

18. A method according to claim 17, wherein the patient activity level is determined from the signal of the accelerometer.

19. A method according to claim 17, further including electrically coupling a band pass filter to said accelerometer, said band pass filter having a range of between 20-70 Hertz for filtering the signal associated with fluid and myocardial accelerations of the heart.

20. A method according to claim 17, wherein the step of identifying heart sounds occurs during a detection window having a predefined duration.

21. A method according to claim 17, wherein the determination of determining whether the identified heart sounds are associated with delivery of the stimulation pulse to the heart includes a step down stimulation protocol.

22. A method according to claim 17, wherein the step of identifying heart sounds further includes identifying heart sounds associated with at least one of S₁ and S₂.

23. A method according to claim 17, wherein the step of identifying heart sounds further includes identifying a heart sound associated with S₁.

24. A method according to claim 17, wherein the step of identifying heart sounds further includes identifying a heart sound associated with S₂.

25. A cardiac rhythm management device capable of functioning in a preset stimulation and/or autocapture mode having preset stimulation rates and timing intervals, said rhythm management device comprising:

a pulse generator that generates a stimulation pulse for delivery to at least one of an atrium and a ventricle of a heart;

an accelerometer positioned near the heart, wherein said accelerometer transmits a global signal associated with fluid and myocardial accelerations of the heart; and

a controller electrically coupled to said pulse generator and said accelerometer, said controller including a device for identifying heart sounds from the signal of the accelerometer over corresponding cardiac cycles and a device for determining whether an identified heart sound is associated with delivery of the stimulation pulse to the heart;

wherein said controller includes a detection window having a predefined duration;

wherein said controller determines a maximum output of the accelerometer signal for at least one cardiac cycle; and

wherein a center of the detection window is aligned with a determined maximum output of the accelerometer signal during a first cardiac cycle.

26. A cardiac rhythm management device according to claim 25, wherein said accelerometer is electrically coupled to a band pass filter having a range of between 20-70 Hertz for filtering the signal associated with fluid and myocardial accelerations of the heart.

27. A cardiac rhythm management device according to claim 25, wherein said means for determining whether an identified heart sound is associated with delivery of the stimulation pulse to the heart includes a step down stimulation protocol.

28. A cardiac rhythm management device according to claim 25, wherein the identified heart sound is associated with at least one of S₁ and S₂.

29. A cardiac rhythm management device according to claim 25, wherein the identified heart sound is associated with S₁.

30. A cardiac rhythm management device according to claim 25, wherein the identified heart sound is associated with S₂.

31. A cardiac rhythm management device capable of functioning in a preset stimulation and/or autocapture mode having preset stimulation rates and timing intervals, said rhythm management device comprising:

a pulse generator that generates a stimulation pulse for delivery to at least one of an atrium and a ventricle of a heart;

an accelerometer positioned near the heart, wherein said accelerometer transmits a global signal associated with fluid and myocardial accelerations of the heart; and

a controller electrically coupled to said pulse generator and said accelerometer, said controller including a device for identifying heart sounds from the signal of the accelerometer over corresponding cardiac cycles and a device for determining whether an identified heart sound is associated with delivery of the stimulation pulse to the heart; and

wherein said controller determines a patient activity level and terminates the determination whether the identified heart sound is associated with delivery of the stimulation pulse to the heart when the patient activity level exceeds a predetermined amount.

32. A cardiac rhythm management device according to claim 31, wherein the patient activity level is determined from the signal of the accelerometer.