System for processing a subject's electrical activity measurements

• US 6,654,632 B2
• Filed: 10/15/2001
• Issued: 11/25/2003
• Est. Priority Date: 07/06/2000
• Status: Expired due to Fees

• Current Assignee: Algodyne Limited
• Original Assignee: Algodyne Limited
• Inventors: Lewinsky, Reuven, Lange, Daniel H.
• Primary Examiner(s): Nasser, Robert L.
• Assistant Examiner(s): Mallari, Patricia C
• Application Number:
  US09/977,597
• Publication Number:
  US 20020138018A1
• Time in Patent Office: 771 Days
• Field of Search: 600/544-545
• US Class Current: 600/544
• CPC Class Codes: A61B 5/1106 to assess neuromuscular blockade, e.g. to estimate depth of anaesthesia
• CPC Class Codes: A61B 5/291 for electroencephalography [EEG]
• CPC Class Codes: A61B 5/4824 Touch or pain perception evaluation A61B5/4821 takes precedence
• CPC Class Codes: A61B 5/483 by thermal stimulation
• CPC Class Codes: A61B 5/6833 Adhesive patches

Abstract

Methods, apparatuses and systems relating to the objective measurement of the subjective perception of pain in a subject are disclosed. In one aspect, a system for objectively measuring a subjective perception of pain by a subject comprises a plurality of electrodes, including a left channel electrode and a right channel electrode. The plurality of electrodes measures electrical activity at a respective plurality of sites on the subject to generate at least two sets of electrical activity measurements. The system further comprises a processor for processing the at least two sets of electrical activity measurements into at least two normalized signals, and comparing the at least two normalized signals to each other to identify the presence of pain in the subject.

Claims

1. A system for processing electrical activity measurements taken from a subject comprising:

(a) a memory for storing the electrical activity measurements;

(b) a processor connected to the memory for processing the electrical activity measurements into a normalized signal, and determining a level value representative of an objective pain measurement for the normalized signal within a predetermined range of frequencies, wherein said electrical activity measurements comprise at least two sets of electrical activity measurements, and the processor for processing the at least two sets of electrical activity measurements into the at least two normalized signals, and for comparing the at least two normalized signals to each other to detect the experience of pain by the subject, wherein the processor determines a confidence value associated with the level value based on the processor comparing the at least two normalized signals, and wherein the processor determines a pain value based on the level value and the confidence value.

2. A system for processing electrical activity measurements taken from a subject comprising:

(a) a signal preparer for normalizing the electrical activity measurements;

(b) a pain intensity quantifier connected to the signal preparer for processing the normalized signal to determine a pain intensity level;

(c) a pain detector connected to the signal preparer for processing the normalized signal to determine a pain detection level; and

(d) a confidence assessor connected to the pain intensity quantifier and the pain detector for processing the pain detection level and the pain intensity level to determine an output pain level.

3. The system of claim 2, further comprising an output interface connected to the confidence assessor for displaying the output pain level.