Enzymatic preparation of hydroxy fatty acid esters of polyhydric alcohols which are solid at room temperature

• US 6,706,502 B2
• Filed: 10/12/2001
• Issued: 03/16/2004
• Est. Priority Date: 10/12/2000
• Status: Expired due to Fees

• Current Assignee: Evonik Goldschmidt GmbH (Rag-Stiftung)
• Original Assignee: Goldschmidt AG
• Inventors: Lersch, Peter, Hills, Geoffrey, Grüning, Burghard
• Primary Examiner(s): Lilling, Herbert J.
• Application Number:
  US09/976,215
• Publication Number:
  US 20020090686A1
• Time in Patent Office: 886 Days
• Field of Search: 435/134, 435/198
• US Class Current: 435/134
• CPC Class Codes: A61K 8/0229 Sticks
• CPC Class Codes: A61K 8/042 Gels
• CPC Class Codes: A61K 8/375 the alcohol moiety containing more than one hydroxy group
• CPC Class Codes: A61Q 15/00 Anti-perspirants or body deodorants deodorisation of air A61L9/00
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: C07C 69/675 of saturated hydroxy-carboxylic acids
• CPC Class Codes: C12P 7/6436 Fatty acid esters

Abstract

The present invention relates to an enzymatic process for the preparation of hydroxy fatty acid esters which are solid at room temperature and have improved melting behavior. Specifically, the enzymatic process includes reacting di- or polyols having at least two primary and optionally secondary or tertiary, hydroxyl groups, and hydroxy fatty acids and/or hydroxy fatty acid alkyl esters, and optionally, removing water of reaction or alcohol of reaction which forms.

Claims

1. A technical mixture of hydroxy fatty acid esters which are solid at room temperature and have improved melting behavior, prepared by reacting, in the presence of an enzyme, alcohols having the formula HO—

(CH₂—

CH₂—

O), H, wherein x is from 1 to 3 and a fatty acid component selected from hydroxy fatty acids, hydroxy fatty acid alkyl esters and combinations thereof.