Multiparticulate modified release composition

  • US 6,730,325 B2
  • Filed: 05/07/2001
  • Issued: 05/04/2004
  • Est. Priority Date: 11/02/1998
  • Status: Expired due to Term
First Claim
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1. A multiparticulate modified release composition comprising a first population of acitve ingredient-containing particles and at least one subsequent population of active ingredient-containing particles, wherein the acitive ingredient contained in the first population is a drug compound that acts on the central nervous system, and the subsequent population of active ingredient-containing particles further comprises a modified release coating or, alternatively or additionally, a modified release matrix material, such that the composition following oral delivery to a subject delivers the active ingredients in the first and subsequent populations in a pulsatile manner.

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