Implantable drug delivery device with peristaltic pump having retracting roller

• US 6,743,204 B2
• Filed: 04/13/2001
• Issued: 06/01/2004
• Est. Priority Date: 04/13/2001
• Status: Expired due to Term

• Current Assignee: Medtronic Vascular (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Robinson, Reginald D., Luedi, Manfred, Heruth, Kenneth T., Haase, James M., Christenson, Steven R.
• Primary Examiner(s): Look, Edward K.
• Assistant Examiner(s): Fristoe, Jr., John K.
• Application Number:
  US09/834,874
• Publication Number:
  US 20020151846A1
• Time in Patent Office: 1,145 Days
• Field of Search: 604/151, 604/153, 604/131, 417/477.3, 417/477.7, 417/477.1, 417/474, 417/476, 417/423.6
• US Class Current: 604/151
• CPC Class Codes: A61M 2205/0266 Shape memory materials
• CPC Class Codes: A61M 5/14232 Roller pumps
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: F04B 43/1253 by using two or more rollers as squeezing elements, the rollers moving on an arc of a circle during squeezing
• CPC Class Codes: F04B 43/1276 Means for pushing the rollers against the tubular flexible member
• CPC Class Codes: Y10T 29/4924 Scroll or peristaltic type

Abstract

An implantable drug infusion device includes a pump tube for holding a liquid to be pumped. A race is configured to support the pump tube. A roller assembly is configured to compress the tube against the race at one or more points along the path, and the roller assembly includes at least one roller and a hub. A drive assembly drives the roller assembly relative to the tube along the path so as to move the liquid through the tube. A retracting roller is operably connected to the hub and/or one or more adjacent rollers to permit retraction of the roller during installation of the pump tube between the roller and the race.

Claims

1. An implantable drug infusion device comprising, in combination:

a pump tube for holding a liquid to be pumped;

a race configured to support the tube along a path, the race having a center;

a roller assembly configured to compress the tube against the race at one or more points along the path, the roller assembly including at least two retracting rollers and a hub, the hub having a center;

a drive assembly to drive the roller assembly relative to the tube along the path to move the liquid through the tube,

each retracting roller operably and pivotally connected to the hub by a corresponding retracting roller arm and a corresponding biasing member to permit angular retraction of each retracting roller in relation to the pump tube during installation of the pump tube between each retracting roller and the race, wherein the retracting rollers and the hub form a triangle, each corresponding retracting roller arm and corresponding biasing member forming an angle, each retracting roller located at one end of its corresponding retracting roller arm, the center of the hub substantially coinciding with the center of the race, the load of the rollers on the tube being substantially uniform after installation of the pump tube between the retracting rollers and the race.

2. The implantable drug infusion device of claim 1, wherein each biasing member comprises a coil spring.

3. The implantable drug infusion device of claim 1, wherein the biasing member is from a material selected from the group consisting of cobalt, stainless steel or nitinol shape memory alloy.

4. The implantable drug infusion device of claim 1, wherein the race includes an inlet ramp and an outlet ramp.

5. The implantable drug infusion device of claim 4, wherein the inlet ramp has an arcuate geometry.

6. The implantable drug infusion device of claim 4, wherein the outlet ramp has an arcuate geometry.

7. The implantable drug infusion device of claim 1 wherein the roller arm assembly comprises at least three retracting rollers.

8. The implantable drug infusion device of claim 1, further comprising at least one hook on the hub and a pivot pin on at least one retracting roller arm, wherein the pivot pin is captured by the hook.

9. The implantable drug infusion device of claim 8, wherein the device has at least three retracting rollers, and at least three corresponding roller arms and three corresponding hooks.

10. The implantable drug infusion device of claim 1, wherein the drive assembly comprises a drive shaft and a drive gear, the drive gear configured to be rotatably driven by a motor, the drive shaft rotatably driven by the drive gear and rotatably driving the roller assembly.

11. The implantable drug infusion device of claim 10, wherein the drive gear includes a plurality of teeth about a periphery of the drive gear engageable by a gear of a motor assembly.

12. An implantable drug infusion device comprising, in combination:

a bulkhead having a race, the race having a center;

a pump tube having an inlet and an outlet and being positioned within the race;

a roller assembly configured to compress the tube against the race at one or more points along the path, the roller assembly including at least two retracting rollers and a hub, the hub having a center;

a drive assembly to drive the roller assembly relative to the tube along the path to move the liquid through the tube,

each retracting roller operably and pivotally connected to the hub by a corresponding retracting roller arm and a corresponding biasing member to permit angular retraction of each retracting roller in relation to the pump tube during installation of the pump tube between each retracting roller and the race, wherein the retracting rollers and the hub form a triangle, each corresponding retracting roller arm and corresponding biasing member forming an angle, each retracting roller located at one end of its corresponding retracting roller arm, the center of the hub substantially coinciding with the center of the race, the load of the rollers on the tube being substantially uniform after installation of the pump tube between the retracting rollers and the race.

13. The implantable drug infusion device of claim 12 wherein the biasing member comprises a coil spring.

14. The implantable drug infusion device of claim 12, wherein the biasing member is from a material selected from the group consisting of cobalt, stainless steel, or nitinol shape memory alloy.

15. The implantable drug infusion device of claim 12, further comprising a support plate to secure the roller assembly and drive assembly to the bulkhead.

16. The implantable drug infusion device of claim 12, further comprising a motor assembly, the drive assembly driven by the motor assembly.

17. An implantable drug infusion device comprising, in combination:

a bulkhead having a race, a first chamber, and a second chamber, the race having a center;

a pump tube having an inlet and an outlet and being positioned within the race;

a motor assembly positioned within the first chamber; and

a pumphead assembly positioned within the second chamber, the motor assembly driving the pumphead assembly, the pumphead assembly comprising

a roller assembly having a hub, the hub having a center, and at least two retracting rollers, each retracting roller operably and pivotally connected to the hub by a corresponding retracting roller arm and a corresponding biasing member to permit angular retraction of each retracting roller during installation of a pump tube between each retracting roller and the race; and

a drive assembly to drive the roller assembly relative to the tube along the path so each retracting roller compresses the tube to move a liquid through the tube after installation of the pump tube between the retracting rollers and the race,

wherein the retracting rollers and the hub form a triangle, each corresponding retracting roller arm and corresponding biasing member forming an angle, the center of the hub substantially coinciding with the center of the race, the load of the rollers on the tube being substantially uniform after installation of the pump tube between the retracting rollers and the race.

18. The implantable drug infusion device of claim 17 wherein the roller assembly has three retracting roller arms.

19. The implantable drug infusion device of claim 17, wherein the pumphead assembly further comprises a support plate secured to the bulkhead.

20. The implantable drug infusion device of claim 17, wherein the race includes an inlet ramp and an outlet ramp, the inlet ramp and outlet ramp each having an arcuate geometry.

21. The implantable drug infusion device of claim 17, wherein the biasing member is from a material selected from the group consisting of cobalt, stainless steel, or nitinol shape memory alloy.

22. The implantable drug infusion device of claim 17, wherein the biasing member is a spring.

23. An implantable drug infusion device comprising, in combination:

a bulkhead having a race, a first chamber, and a second chamber;

a pump tube having an inlet and an outlet and being positioned within the race, the race configured to support the tube along a path, the race having a center;

a motor assembly positioned within the first chamber; and

a pumphead assembly positioned within the second chamber, the motor assembly driving the pumphead assembly, the pumphead assembly comprising

a roller assembly having a hub, the hub having a center, and at least two retracting roller housings operably connected by a biasing member to each other to permit retraction of a roller corresponding to each roller housing during installation of a pump tube between the roller and the race wherein the rollers and the hub form a triangle; and

a drive assembly to drive the roller assembly relative to the tube along the path so the roller compresses the tube to move a liquid through the tube,

wherein the retracting rollers and the hub form a triangle, the center of the hub substantially coinciding with the center of the race, the load of the rollers on the tube being substantially uniform after installation of the pump tube between the retracting rollers and the race.

24. The implantable drug infusion device of claim 23, wherein the biasing member is a spring.

25. The implantable drug infusion device of claim 24 wherein the roller assembly has three retracting roller housings operably connected to each other to permit retraction of a roller corresponding to each roller housing during installation of a pump tube between the roller and the race.

26. The implantable drug infusion device of claim 25, wherein the biasing members that operably connect the roller housings are springs.

27. The implantable drug infusion device of claim 23, wherein the biasing member is from a material selected from the group consisting of cobalt, stainless steel or nitinol shape memory alloy.

28. An implantable drug infusion device comprising, in combination:

a pump tube for holding a liquid to be pumped;

a race configured to support the tube along a path;

a roller assembly configured to compress the tube against the race at one or more points along the path, the roller assembly including at least one retracting roller and hub;

a drive assembly to drive the roller assembly relative to the tube along the path to move the liquid through the tube,

the retracting roller operably connected to the hub or at least one adjacent roller to permit retraction of the roller during installation of the pump tube between the roller and the race,

wherein the roller assembly comprises at least one retracting roller arm pivotally connected to the hub, each retracting roller arm having a roller secured thereto and operably connected to the hub, further comprising at least one hook on the hub and a pivot pin on the retracting roller arm, wherein the pivot pin of the retracting roller arm is captured by a hook.

29. The implantable drug infusion device of claim 28, wherein the biasing member is from a material selected from the group consisting of cobalt, stainless steel, or nitinol shape memory alloy.

30. An implantable drug infusion device comprising, in combination:

a pump tube for holding a liquid to be pumped;

a race configured to support the tube along a path;

a roller assembly configured to compress the tube against the race at one or more points along the path, the roller assembly including at least one retracting roller and hub;

a drive assembly to drive the roller assembly relative to the tube along the path to move the liquid through the tube,

the retracting roller operably connected to at least one adjacent roller to permit retraction of the retracting roller during installation of the pump tube between the roller and the race,

wherein the drive assembly comprises a shaft and a drive gear, the drive gear configured to be rotatably driven by a motor, the shaft driven by the drive gear and rotatably driving the roller assembly.

31. The implantable drug infusion device of claim 30, wherein the drive gear includes a plurality of teeth about a periphery of the drive gear engageable by a gear of a motor assembly.

32. An implantable drug infusion device comprising, in combination:

a bulkhead having a race, the race having a center;

a pump tube having an inlet and an outlet and being positioned within the race;

a roller assembly configured to compress the tube against the race at one or more points along the path, the roller assembly including at least two retracting rollers and hub, the hub having a center;

a drive assembly to drive the roller assembly relative to the tube along the path to move the liquid through the tube,

each retracting roller operably and pivotally connected to the hub by a retracting roller arm and a corresponding biasing member to permit angular retraction of each retracting roller in relation to the pump tube during installation of the pump tube between each roller and the race,

and further comprising a support plate to secure the roller assembly and drive assembly to the bulkhead,

wherein the retracting rollers and the hub form a triangle, each corresponding retracting roller arm and corresponding biasing member forming an angle, each retracting roller located at one end of its corresponding retracting roller arm, the center of the hub substantially coinciding with the center of the race, the load of the rollers on the tube being substantially uniform after installation of the pump tube between the retracting rollers and the race.

33. The implantable drug infusion device of claim 32, wherein the biasing member is from a material selected from the group consisting of cobalt, stainless steel, or nitinol shape memory alloy.

34. An implantable drug infusion device comprising, in combination:

a bulkhead having a race, a first chamber, and a second chamber;

a pump tube having an inlet and an outlet and being positioned within the race, the race having a center;

a motor assembly positioned within the first chamber; and

a pumphead assembly positioned within the second chamber, the motor assembly driving the pumphead assembly, the pumphead assembly comprising

a roller assembly having a hub, the hub having a center, and at least two retracting roller, each retracting roller operably and pivotally connected to the hub by a corresponding retracting roller arm and a corresponding biasing member to permit angular retraction of each retracting roller during installation of a pump tube between each retracting roller and the race; and

a drive assembly to drive the roller assembly relative to the tube along the path so each retracting roller compresses the tube to move a liquid through the tube after installation of the pump tube between the retracting rollers and the race

wherein the retracting rollers and the hub form a triangle, each corresponding retracting roller arm and corresponding biasing member forming an angle, the center of the hub substantially coinciding with the center of the race, the load of the rollers on the tube being substantially uniform after installation of the pump tube between the retracting rollers and the race, and

wherein the pumphead assembly further comprises a support plate secured to the bulkhead.