Compositions and methods for enhancing corticosteroid delivery

  • US 6,765,001 B2
  • Filed: 12/21/2001
  • Issued: 07/20/2004
  • Est. Priority Date: 12/21/2001
  • Status: Expired due to Term
First Claim
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1. A composition comprisingOne or more corticosteroids, wherein one corticosteroid comprises fluocinonide;

  • Two or more penetration enhancers selected from the group consisting of diisopropyl adipate, dimethyl isosorbide, propylene glycol, 1,2,6-hexapetriol, and benzyl alcohol; and

    one or more of the group consisting of solvents and emulsifiers, wherein the penetration enhancers are present in a ratio to a total of the penetration enhancers, and solvents and emulsifiers of at least about 0.90.

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