Non-invasive apparatus system for monitoring autonomic nervous system and uses thereof
First Claim
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1. A non-invasive apparatus system to monitor the autonomic nervous system comprising:
- (a) a sensor for measuring artery sphygmograms or heart potential signals to form electric waves representing the artery sphygmograms or heart potential signals; and
(b) an analyzer for receiving the electric waves from said sensor, wherein heart rate variability parameters in the electric waves are calculated by Fourier Transform or Fast Fourier Transform methods and spectral analysis;
wherein said analyzer calculates the degree of the functional changed side effects caused by drugs, to monitor aging of the autonomic nervous system and tracing therapeutic effect thereof, based on said heart rate variability parameters.
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Abstract
A non-invasive apparatus system for monitoring autonomic nervous system, and its uses in monitoring autonomic nervous system functional change side effects caused by drugs and monitoring the aging of autonomic nervous system and tracing therapeutic effect thereof.
33 Citations
11 Claims
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1. A non-invasive apparatus system to monitor the autonomic nervous system comprising:
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(a) a sensor for measuring artery sphygmograms or heart potential signals to form electric waves representing the artery sphygmograms or heart potential signals; and
(b) an analyzer for receiving the electric waves from said sensor, wherein heart rate variability parameters in the electric waves are calculated by Fourier Transform or Fast Fourier Transform methods and spectral analysis;
wherein said analyzer calculates the degree of the functional changed side effects caused by drugs, to monitor aging of the autonomic nervous system and tracing therapeutic effect thereof, based on said heart rate variability parameters.- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method for monitoring autonomic nervous system functional change side effects caused by drugs, which comprises the utilization of a non-invasive apparatus system in monitoring and calculating the heart rate variability parameters before and after taking the drug;
- wherein the value of change in the heart rate variability parameter being smaller than a predetermined value represents that the drug does not cause side effect to the autonomic nervous system, and the value of change in the heart rate variability parameter being between two predetermined values represents that the drug has induced a certain degree of functional change to the autonomic nervous system, and the value of change in the heart rate variability parameter being greater than a predetermined value represents that the drug has induced severe functional change to the autonomic nervous system; and
the non-invasive apparatus system includes;(a) a sensor for measuring artery sphygmograms or heart potential signals to form electric waves representing the artery sphygmograms or heart potential signals; and
(b) an analyzer for receiving the electric waves from said sensor, wherein heart rate variability parameters in the electric waves are calculated by Fourier Transform or Fast Fourier Transform method and spectral analysis.
- wherein the value of change in the heart rate variability parameter being smaller than a predetermined value represents that the drug does not cause side effect to the autonomic nervous system, and the value of change in the heart rate variability parameter being between two predetermined values represents that the drug has induced a certain degree of functional change to the autonomic nervous system, and the value of change in the heart rate variability parameter being greater than a predetermined value represents that the drug has induced severe functional change to the autonomic nervous system; and
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11. A method for monitoring aging of autonomic nervous system and tracing therapeutic effect thereof, which comprises the utilization of a non-invasive apparatus system in monitoring and calculating the heart rate variability parameters, and the comparison of the parameters with those of normal people at the same age and sex;
- wherein the non-invasive apparatus system includes;
(a) a sensor for measuring artery sphygmograms or heart potential signals to form electric waves representing the artery sphygmograms or heart potential signals; and
(b) an analyzer for receiving the electric waves from said sensor, wherein heart rate variability parameters in the electric waves are calculated by Fourier Transform or Fast Fourier Transform method and spectral analysis.
- wherein the non-invasive apparatus system includes;
Specification