System for treating kidney disease in diabetic and non-diabetic patients

  • US 6,821,527 B2
  • Filed: 03/19/2003
  • Issued: 11/23/2004
  • Est. Priority Date: 06/16/2000
  • Status: Expired due to Term
First Claim
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1. A system for treating kidney disease in diabetic and non-diabetic patients through an intravenous site administering a pulse of insulin to a patient comprising:

  • a) a means for determining a steady baseline respiratory quotient of the patient and obtaining a subsequent respiratory quotient every 30 minutes, the steady baseline respiratory quotient being two identical consecutive respiratory quotients less than 0.90 measured five minutes apart, b) a liquid or food containing 60 to 100 grams of glucose, the liquid or food containing 60 to 100 grams of glucose being consumed by the patient, and c) a means for administering intravenously the pulse of insulin at a regular interval of time until the subsequent respiratory quotient shows an improvement over the steady baseline respiratory quotient, the improvement being a respiratory quotient of 0.90 or greater, the subsequent respiratory quotient improvement over the steady baseline respiratory quotient being a measurement of sufficient insulin pulses to achieve a stabilization or decrease in 24-hour urinary protein excretion or a stabilization or increase in creatinine clearance.

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