Ophthalmic compositions containing galactomannan polymers and borate
DCFirst Claim
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1. An ocular lubricant composition, comprising:
- 0.1 to 5% (w/v) of one or more borate compounds selected from the group consisting of boric acid and pharmaceutically acceptable salts thereof;
0.05 to 5% (w/v) of one or more galactomannan polysaccharides having linear chains of (1-4)-β
-D-mannopyranosyl units with α
-D-galactopyranosyl units attached by (1-6) linkages; and
water;
wherein the composition does not contain a pharmaceutically active agent.
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Abstract
The present invention is directed to ophthalmic compositions containing a gelling amount of a combination of galactomannan polysaccharides and borates. The compositions gel or partially gel upon administration to the eye. The present invention also discloses methods of topical ophthalmic administration of the compositions to the eye.
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9 Claims
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1. An ocular lubricant composition, comprising:
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0.1 to 5% (w/v) of one or more borate compounds selected from the group consisting of boric acid and pharmaceutically acceptable salts thereof;
0.05 to 5% (w/v) of one or more galactomannan polysaccharides having linear chains of (1-4)-β
-D-mannopyranosyl units with α
-D-galactopyranosyl units attached by (1-6) linkages; and
water;
wherein the composition does not contain a pharmaceutically active agent. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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Specification