Monitoring of physiological analytes

  • US 6,850,790 B2
  • Filed: 05/14/2003
  • Issued: 02/01/2005
  • Est. Priority Date: 05/13/1998
  • Status: Expired due to Term
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First Claim
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1. A method for measuring an amount or concentration of an analyte present in a biological system, said method comprisingcontacting one or more samples, comprising said analyte, with a sensing electrode;

  • obtaining a measurement signal from each sample comprising analyte using said sensing electrode that is related to analyte amount or concentration in said biological system; and

    applying one or more processes for selectively favoring analyte-specific signal components over signal components due to interfering species, said processes selected from the group consisting of (a) selective electrochemical detection process that is performed during said obtaining, said process comprising contacting each sample with an electrochemical sensing electrode that is maintained at a potential less than about 0.6V, (b) a purge step that is performed before and/or after said obtaining, wherein said purge step substantially removes residual signal components from the sensing electrode, and (c) any combinations thereof.

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