Dual-energy radiography process differentiating bone tissues, lean tissues and fatty tissues

• US 6,857,640 B2
• Filed: 12/09/2002
• Issued: 02/22/2005
• Est. Priority Date: 12/07/2001
• Status: Expired due to Term

• Current Assignee: Commissariat a L'Energie Atomique (AES Corporation)
• Original Assignee: Commissariat a L'Energie Atomique (AES Corporation)
• Inventors: Robert-Coutant, Christine, Dinten, Jean-Marc, Herve, Lionel
• Primary Examiner(s): Church, Craig E.
• Assistant Examiner(s): Kiknadze, Irakli
• Application Number:
  US10/314,210
• Publication Number:
  US 20030133538A1
• Time in Patent Office: 806 Days
• Field of Search: 378/54, 378/53, 378/5, 378/37, 378/98.9
• US Class Current: 378/53
• CPC Class Codes: A61B 6/482 involving multiple energy imaging
• CPC Class Codes: A61B 6/505 for diagnosis of bone

Abstract

This radiography process utilizes dual-energy rays and comprises, in order to differentiate bone, lean and fatty tissues at the same time, an improvement consisting in assessing the total length penetrated by each ray while correcting the errors which may be produced by internal gas pockets. One proceeds as follows: selection of certain rays which have not penetrated bone tissues; calculation of the thicknesses of lean and fatty tissues penetrated by these rays according to the two attenuations, the sum of these two thicknesses being the length of attenuation; estimation of the length of attenuation elsewhere, in particular by means of interpolations; and calculation of the thicknesses of the three categories of tissues penetrated according to this total length of attenuation and the two attenuations.

Claims

1. A radiography process, comprising:

irradiating an organism with dual energy rays;

selecting rays which have not penetrated bone tissues;

calculating a sum of a thickness of lean tissue and the thickness of fatty tissue penetrated by said selected rays according to an attenuation sustained at said thickness of said lean tissue and said thickness of said fatty tissue;

calculating at least one total length penetrated by said selected rays in the organism which is equal to said sum of thickness of said lean tissue and said thickness of said fatty tissue for said selected rays; and

estimating at least one other total length penetrated by said dual energy rays by interpolation between said sum of thickness of said lean tissue and said fatty tissue and a sum of thicknesses for rays different from said selected rays;

calculating the thicknesses of bone tissues, lean tissues and fatty tissues penetrated by said dual energy rays according to the attenuations sustained at the two energies and the total lengths.

2. The method according to claim 1, wherein a conical beam is used for said irradiating.

3. The method according to claim 1, wherein the thicknesses or masses of said bone tissues, lean tissues and fatty tissues penetrated by said dual energy rays are calculated using the following equation system:

$\begin{array}{ccc}\left({\mathrm{\mu <br><br>}}_{1<br><br>m}<br><br>\text{\hspace{1em}<br><br>}<br><br>{\mathrm{\mu <br><br>}}_{1<br><br>g}<br><br>\text{\hspace{1em}<br><br>}<br><br>{\mathrm{\mu <br><br>}}_{1<br><br>\mathrm{os}}\right)& \left(M_m\right)& \left(X_1\right)\\ \left({\mathrm{\mu <br><br>}}_{2<br><br>m}<br><br>\text{\hspace{1em}<br><br>}<br><br>{\mathrm{\mu <br><br>}}_{2<br><br>g}<br><br>\text{\hspace{1em}<br><br>}<br><br>{\mathrm{\mu <br><br>}}_{2<br><br>\mathrm{os}}\right)& \left(M_g\right)=& \left(X_2\right)\\ \left(I/{\mathrm{\rho <br><br>}}_m<br><br>\text{\hspace{1em}<br><br>}<br><br>I/{\mathrm{\rho <br><br>}}_g<br><br>\text{\hspace{1em}<br><br>}<br><br>I/{\mathrm{\rho <br><br>}}_{\mathrm{os}}\right)& \left(M_{\mathrm{os}}\right)& \left(L\right)\end{array}$

wherein

M_m, M_g and M_os designate the masses by unit of area, in g/cm², of lean, fatty and bone tissues penetrated by the rays;

X₁, X₂ and L designate the attenuations of the radiation, expressed by the logarithm of the intensity ratios of the original radiation Io and of the radiation I received by the detector involved;

X=In (I_o/I), and the total length of attenuation;

μ

_1m, μ

_1g, μ

_1os, μ

_2m, μ

_2g and μ

_2os designate the coefficients of attenuation for the two energies, of the lean, fatty and bone tissues in cm/g², and

ρ

_m, ρ

_g and ρ

_os are the densities of the lean, fatty and bone tissues.

4. The method according to claim 3, wherein said equation system yields the values of M_m, M_g and M_os, which can be correlated with the penetrated thicknesses of the lean, fatty and bone tissues I_m, I_g, and I_os by the following formulas I_m=M_m/ρ

_m,I_g=M_g/ρ

_g and I_os=M_os/ρ

_os.

5. The method according to claim 1, wherein the total penetrated length L is expressed by a linear function of the measurements X₁ and X₂.

6. The method according to claim 1, wherein said dual energy rays are polychromatic.

7. The method according to claim 1, wherein the total penetrated length L is expressed by the following polynomial function:

L=α

X₁+β

X₂+γ

X²₁+δ

X₁X₂+ε

X²₂;

wherein α

, β

, γ

, δ and

ε

are coefficients which are assessed by measurements of irradiation through wedges.

8. An apparatus, comprising:

a source for dual energy rays; and

at least one detector;

wherein said apparatus performs the method according to claim 1 for a differentiation among bone tissues, lean tissues and fatty tissues of an organism penetrated by dual energy rays and for estimations of thicknesses of the lean tissues, bone tissues and fatty tissues penetrated by the dual energy rays.