Hydrogel from polysiloxane-containing urethane prepolymer, tris (trimethylsiloxy) silylpropyl methacrylate, and a hydrophilic comonomer
First Claim
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1. A hydrogel material that is a polymerization product of a comonomer mixture comprising:
- (a) a polysiloxane-containing urethane prepolymer;
(b) tris(trimethylsiloxy)silylpropyl methacrylate; and
(c) at least one hydrophilic comonomer selected from the group consisting of N-vinyl-2-pyrrolidinone and N,N-dimethylacrylamide, wherein the hydrogel material has a water content of at least 22.4 weight percent.
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Abstract
A polyurethane based prepolymer is provided and useful in biomedical devices which provides high oxygen permeability and superior physical properties. A hydrogel is produced from a comonomer mixture containing a polysiloxane-containing urethane prepolymer, tris(trimethylsiloxy)-silylpropyl methacrylate and a hydrophilic comonomer. The hydrogel is especially useful for biomedical materials such as contact lenses and implants.
157 Citations
13 Claims
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1. A hydrogel material that is a polymerization product of a comonomer mixture comprising:
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(a) a polysiloxane-containing urethane prepolymer;
(b) tris(trimethylsiloxy)silylpropyl methacrylate; and
(c) at least one hydrophilic comonomer selected from the group consisting of N-vinyl-2-pyrrolidinone and N,N-dimethylacrylamide, wherein the hydrogel material has a water content of at least 22.4 weight percent. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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Specification