Method of treating eye infections with azithromycin

• US 6,861,411 B1
• Filed: 11/25/1998
• Issued: 03/01/2005
• Est. Priority Date: 12/02/1997
• Status: Expired due to Term

• Current Assignee: Pfizer Inc.
• Original Assignee: Pfizer Inc.
• Inventors: Ahmed, Imran
• Primary Examiner(s): Peselev, Elli
• Application Number:
  US09/200,119
• Time in Patent Office: 2,288 Days
• Field of Search: 514/29, 536/7.4, 536/7.3
• US Class Current: 514/29
• CPC Class Codes: A61K 31/7048 having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin , digitoxin or digoxin

Abstract

The invention features methods and compositions for treating ocular infections. The method comprises topically administering to an eye of an animal in need of such treatment an ocular infection-treating amount of azithromycin.

Claims

1. A method of treating an ocular infection, comprising topically administering to an eye of an animal in need of such treatment an ocular infection-treating amount of azithromycin.

2. A method as defined in claim 1 wherein said azithromycin is present in a composition comprising a pharmaceutically acceptable topical vehicle at a concentration of from 0.1 to 2.5 weight percent.

3. A method as defined in claim 2, wherein said composition is administered once daily.

4. A method as defined in claim 1, wherein said animal is a human.

5. A method as defined in claim 2, wherein said azithromycin concentration is from 0.2 to 2.0 weight %.

6. A method as defined in claim 5, wherein said azithromycin concentration is 0.5 weight %.

7. A method as defined in claim 1, wherein said azithromycin is in the form of the dihydrate.

8. A method as defined in claim 1, wherein said ocular infection is trachoma.