Phototherapeutic treatment methods and apparatus

• US 6,866,678 B2
• Filed: 12/10/2002
• Issued: 03/15/2005
• Est. Priority Date: 12/10/2002
• Status: Expired due to Fees

• Current Assignee: International Technology Center
• Original Assignee: InterDigital, Inc.
• Inventors: McGuire, Gary E., Shenderova, Olga
• Primary Examiner(s): Gibson, Roy D.
• Assistant Examiner(s): Johnson, III, Henry M
• Application Number:
  US10/315,420
• Publication Number:
  US 20040111132A1
• Time in Patent Office: 826 Days
• Field of Search: 128/898, 607 88- 94, 313502-506
• US Class Current: 607/88
• CPC Class Codes: A61N 2005/0652 Arrays of diodes
• CPC Class Codes: A61N 2005/0653 Organic light emitting diodes
• CPC Class Codes: A61N 5/0616 Skin treatment other than tanning
• CPC Class Codes: A61N 5/062 Photodynamic therapy, i.e. excitation of an agent
• CPC Class Codes: A61N 5/0621 Hyperbilirubinemia, jaundice treatment

Abstract

A thin film electroluminescent (TFEL) phototherapy device based on high field electroluminescence (HFEL) or from organic light emitting devices (OLED), consistent with certain embodiments of the present invention has a battery and a charging circuit coupled to the battery, so that when connected to a source of current acts to charge the battery. A TFEL panel produces light when voltage from the power source (battery or AC source) is applied. A processor such as a microprocessor is used to control the application of voltage from the power source to the TFEL panel under control of a control program. A housing is used to contain the battery, the charging circuit and the processor and carry the TFEL panel on an outer surface thereof. In one embodiment, the housing incorporates a removable cover that uncovers a household electrical plug useful for supplying charging current to the charger. In use, a method of carrying out phototherapy, consistent with certain embodiments of the invention involves diagnosing a condition of an affected area of tissue that can be treated with phototherapy. A treatment protocol is determined including, for example, a treatment light intensity, a treatment time, a light modulation characteristic and a treatment light wavelength suitable for treating the condition. The affected area is then irradiated with light from the TFEL panel in accord with the treatment protocol.

Claims

1. An electroluminescent phototherapy apparatus, comprising:

a thin film electroluminescent (TFEL) panel that produces light radiation when a voltage greater than a prescribed voltage is applied thereto;

the TFEL panel having a light emitting surface that produces light radiation for delivery to a patient; and

control means, for controlling phototherapeutic parameters for patient exposure to the phototherapeutic light radiation.

2. The phototherapy apparatus according to claim 1, wherein the control means comprises a processor that controls the application of voltage from a voltage source to the TFEL panel under control of a control program.

3. The phototherapy apparatus according to claim 2, wherein the processor further controls a spectral output from the TFEL panel.

4. The phototherapy apparatus according to claim 2, wherein the processor further controls a light power density from the TFEL panel.

5. The phototherapy apparatus according to claim 2, wherein the voltage source comprises a battery.

6. The phototherapy device according to claim 2, further comprising a user interface for entering control information for use by said processor.

7. The phototherapy device according to claim 2, wherein the processor controls at least on of exposure time, light power density, light modulation and light spectrum.

8. The phototherapy apparatus according to claim 1, wherein the TFEL panel comprises a sandwich of electrodes surrounding an active thin film electroluminescent material that produce a light spectrum with at least one wavelength characteristic.

9. The phototherapy apparatus according to claim 8, wherein the active thin film electroluminescent material is doped with a dopant to produce light emissions at a wavelength determined by the dopant.

10. The phototherapy apparatus according to claim 8, wherein the active thin film electroluminescent material is an organic material which is undoped.

11. The phototherapy apparatus according to claim 1, wherein the TFEL panel comprises an inorganic TFEL device having an inorganic active layer that is sandwiched between two insulators and further sandwiched between two conductors, and wherein one of the two conductors is transparent.

12. The phototherapy apparatus according to claim 1, wherein the TFEL panel comprises an organic TFEL device having an organic active layer that is sandwiched between two conductors, and wherein one of the two conductors is transparent, and further having a hole injection layer adjacent the organic active layer.

13. The phototherapy apparatus according to claim 1, wherein the TFEL panel comprises an organic TFEL device having an organic active layer that is sandwiched between two conductors, and wherein one of the two conductors is transparent, and further having an electron injection layer adjacent the organic active layer.

14. The phototherapy apparatus according to claim 1, wherein the TFEL panel comprises an organic TFEL device having an organic active layer that is sandwiched between two conductors, and wherein one of the two conductors is transparent, and further having a hole blocking layer adjacent the organic active layer.

15. The phototherapy apparatus according to claim 1, wherein the TFEL panel comprises an organic TFEL device having an organic active layer that is sandwiched between two conductors, and wherein one of the two conductors is transparent, and further having an electron blocking layer adjacent the organic active layer.

16. The phototherapy apparatus according to claim 1, wherein the TFEL panel comprises an organic TFEL device having an organic active layer that is sandwiched between two conductors, and wherein the organic active layer is doped with a dopant to produce light emissions at a wavelength determined by the dopant.

17. The phototherapy apparatus according to claim 1, further comprising a fiber optic cable coupled to the TFEL panel.

18. The phototherapy apparatus according to claim 17, wherein the fiber optic cable forms part of a catheter.

19. The phototherapy apparatus according to claim 1, further comprising a patient support structure, and wherein the TFEL panel is affixed in proximity to the patient support structure to deliver light to an exposed area of the patient'"'"'s skin when the patient is supported by the support structure.

20. The phototherapy apparatus according to claim 19, wherein the support structure comprises a crib.

21. The phototherapy apparatus according to claim 1, wherein the control means comprises a switch for manual control of actuation of the TFEL panel.

22. The phototherapy apparatus according to claim 1, wherein the control means stores treatment protocols for a variety of conditions treatable with the phototherapy apparatus.

23. An electroluminescent phototherapy apparatus, comprising:

a thin film electroluminescent (TFEL) panel having a plurality of electrodes on one surface thereof that are individually addressable to produce light from an addressed segment of the panel when a voltage greater than a prescribed voltage is applied thereto;

the TFEL panel having an electroluminescent core that is doped using a first dopant in a first segment thereof and doped using a second dopant in a second segment thereof;

the TFEL panel having a light emitting surface that produces light radiation for delivery to a patient; and

a controller that addresses the multiple electrodes in order to produce light from the first segment at a first wavelength and from the second segment at a second wavelength; and

wherein the controller further controls a phototherapeutic parameter.

24. The electroluminescent phototherapy apparatus according to claim 23, wherein the controller further controls a time that the patient is exposed to the light from at least one of the first and second segments.

25. The electroluminescent phototherapy apparatus according to claim 23, wherein the controller comprises a processor that controls the application of voltage from a voltage source to the TFEL panel under control of a control program.

26. The electroluminescent phototherapy apparatus according to claim 23, having a plurality of segments arranged in a checkerboard pattern with the first and second dopants occupying alternating segments of the checkerboard pattern, so that light at either of the first and second wavelengths can be delivered to the patient in a substantially uniform manner by illuminating segments of the checkerboard paftern corresponding to segments with one of the first and second dopant.

27. The electroluminescent phototherapy apparatus according to claim 23, having a plurality of segments arranged in a checkerboard pattern with the first and second types of electroluminescent materials occupying alternating segments of the checkerboard pattern, so that light at either of the first and second wavelengths can be delivered to the patient in a substantially uniform manner by illuminating segments of the checkerboard pattern corresponding to segments with one of the first and second types of electroluminescent materials.

28. The electroluminescent phototherapy apparatus according to claim 23, having a plurality of segments arranged in a pattern of alternating columns with the first and second dopants occupying alternating columns, so that light at either of the first and second wavelengths can be delivered to the patient in a substantially uniform manner by illuminating columns corresponding to one of the first and second dopant.

29. The electroluminescent phototherapy apparatus according to claim 23, further comprising a user interface for entering control information for use by said controller.

30. The electroluminescent phototherapy apparatus according to claim 23, wherein the processor controls at least one of exposure time, light intensity, light modulation and light spectrum.

31. The electroluminescent phototherapy apparatus according to claim 23, further comprising a fiber optic cable coupled to the TFEL panel.

32. The electroluminescent phototherapy apparatus according to claim 31, wherein the fiber optic cable forms part of a catheter.

33. The electroluminescent phototherapy apparatus according to claim 23, further comprising a patient support structure, and wherein the TFEL panel is affixed in proximity to the patient support structure to deliver light to an exposed area of the patient'"'"'s skin when the patient is supported by the support structure.

34. The electroluminescent phototherapy apparatus according to claim 33, wherein the support structure comprises a crib.

35. The electroluminescent phototherapy apparatus according to claim 33, wherein the controller stores treatment protocols for a variety of conditions treatable with the phototherapy apparatus.

37. The hand held electroluminescent phototherapy device according to claim 26, further comprising:

a user interface for entering control information for use by said processor.

36. A hand held electroluminescent phototherapy device, comprising:

a battery;

a charging circuit coupled to the battery, so that when connected to a source of current acts to charge said battery;

a thin film electroluminescent (TFEL) panel that produces light when voltage from said battery is applied thereto;

a processor that controls the application of voltage from the battery to the TFEL panel under control of a control program of phototherapeutic parameters;

a housing containing said battery, said charging circuit and said processor therein and carrying said TFEL panel on an outer surface thereof.

38. The hand held electroluminescent phototherapy device according to claim 36, wherein the control information comprises at least one of controls at least on of exposure time, light intensity, light modulation and light spectrum.

39. The hand held electroluminescent phototherapy device according to claim 36, wherein a portion of the light has a wavelength that falls in the infrared spectrum.

40. The hand held electroluminescent phototherapy device according to claim 36, wherein a portion of the light has a wavelength that falls in the visible light spectrum.

41. The hand held electroluminescent phototherapy device according to claim 36, wherein the processor stores treatment protocols for a variety of conditions treatable with the phototherapy apparatus.

42. A method of carrying out phototherapy, comprising:

diagnosing a condition of an affected area of tissue that can be treated with phototherapy;

determining a treatment protocol for the condition; and

irradiating the affected area of tissue with light from a thin film electroluminescent (TFEL) panel in accordance with the treatment protocol.

43. The method according to claim 42, wherein the treatment protocol specifies a treatment light wavelength and a treatment light power density for a treatment time.

44. The method according to claim 42, further comprising selecting a light wavelength from a menu of available wavelengths.

45. The method according to claim 42, wherein a portion of the light has a wavelength that falls in the infrared spectrum.

46. The method according to claim 42, wherein a portion of the light has a wavelength that falls in the visible light spectrum.

47. The method according to claim 42, wherein the determining comprises determining at least one of a light intensity, a light modulation, a treatment time and a treatment light wavelength suitable for treating the condition.

48. The method according to claim 42, further comprising conditioning the tissue irradiated with the light with a photoreactive substance.

49. An electroluminescent phototherapy apparatus, comprising:

a thin film electroluminescent (TFEL) panel that produces light radiation when a voltage greater than a prescribed voltage is applied thereto;

the TFEL panel having a light emitting surface that produces light radiation for delivery to a patient, wherein the TFEL panel comprises a stacked arrangement of TFEL panels;

each TFEL panel in the stack comprising a sandwich of electrodes surrounding an active electroluminescent material;

wherein each of the TEEL panels in the stack has a doped electroluminescent material that doped differently than other TFEL panels in the stack to produce light with differing spectral content at each TFEL panel in the stack; and

control means, for controlling a time that the patient is exposed to the light radiation.

50. An electroluminescent phototherapy apparatus, comprising:

a thin film electroluminescent (TFEL) panel that produces light radiation when a voltage greater than a prescribed voltage is applied thereto;

the TFEL panel having a light emitting surface that produces light radiation for delivery to a patient, wherein the TFEL panel comprises a stacked arrangement of TFEL panels;

each TFEL panel in the stack comprising a sandwich of electrodes surrounding an active electroluminescent material;

wherein each of the TFEL panels in the stack has an electroluminescent material that is different than the electroluminescent material of the other TFEL panels in the stack to produce light with differing spectral content at each TFEL panel in the stack; and

control means, for controlling a time that the patient is exposed to the light radiation.

51. A hand held electroluminescent phototherapy device, comprising:

a battery;

a charging circuit coupled to the battery, so that when connected to a source of current acts to charge said battery;

a thin film electroluminescent (TFEL) panel that produces light when voltage from said battery is applied thereto;

a processor that controls the application of voltage from the battery to the TFEL panel under control of a control program;

a housing containing said battery, said charging circuit and said processor therein and carrying said TFEL panel on an outer surface thereof

a removable cover forming a part of said housing;

a power connector connected to said charging circuit for connection of said charging circuit to said source of current; and

wherein, removal of said removable cover reveals said power connector.

52. A method of carrying out phototherapy, comprising:

diagnosing a condition of an affected area of tissue that can be treated with phototherapy;

determining a treatment protocol for the condition;

irradiating the affected area of tissue with light from a thin film electroluminescent (TFEL) panel in accordance with the treatment protocol; and

wherein the electroluminescent light source is placed in physical contact with the affected area of tissue.

53. An electroluminescent phototherapy apparatus, comprising:

a thin film electroluminescent (TFEL) panel that produces light radiation with peaks in spectral intensity at or above the near infra-red spectrum when a voltage greater than a prescribed voltage is applied thereto;

the TFEL panel having a light emitting surface that produces light radiation for delivery to a patient; and

control means, for controlling a time that the patient is exposed to the light radiation.

54. The electroluminescent phototherapy apparatus according to claim 53, wherein the TFEL panel comprises a sandwich of electrodes surrounding an electroluminescent material, and wherein the electroluminescent material is doped with a dopant having a rare earth element as a component of the dopant.

55. An electroluminescent phototherapy apparatus, comprising:

a thin film electroluminescent (TFEL) panel that produces light radiation when a voltage greater than a prescribed voltage is applied thereto;

the TFEL panel having an unpixelated light emitting surface that produces light radiation for delivery to a patient; and

control means, for controlling a time that the patient is exposed to the light radiation.

56. A method of carrying out phototherapy, comprising:

diagnosing a condition of an affected area of tissue that can be treated with phototherapy;

determining a treatment protocol for the condition; and

irradiating the affected area of tissue with light from a thin film electroluminescent (TFEL) panel in accordance with the treatment protocol, the TFEL panel producing light radiation with peaks in spectral intensity at or above the near infra-red spectrum.

57. The method according to claim 56, wherein the TFEL panel comprises a sandwich of electrodes surrounding an electroluminescent material, and wherein the electroluminescent material is doped with a dopant having a rare earth element as a component of the dopant.

58. A method of carrying out phototherapy, comprising:

diagnosing a condition of an affected area of tissue that can be treated with phototherapy;

determining a treatment protocol for the condition; and

irradiating the affected area of tissue with light from an unpixelated thin film electroluminescent (TFEL) panel in accordance with the treatment protocol.