Combination of a cyclic hexapeptide with antifungal drugs for treatment of fungal pathogens

  • US 6,875,740 B1
  • Filed: 05/24/2000
  • Issued: 04/05/2005
  • Est. Priority Date: 05/31/1999
  • Status: Expired due to Fees
First Claim
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1. A method for the treatment or inhibition of an infectious disease caused by Aspergillus fumigatus, which comprises;

  • administering an effective amount of a lipopeptide compound [I] of the following formula;

    embedded imagewherein R1 is an acyl group, R2 is hydrogen or hydroxy and R3 is hydrogen or hydroxy, or a pharmaceutically acceptable salt thereof, in combination with Amphotericin B, Itraconazole, Nikkomycin X or Flucytosine.

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