Microfluidic system including a bubble valve for regulating fluid flow through a microchannel

  • US 6,877,528 B2
  • Filed: 06/24/2002
  • Issued: 04/12/2005
  • Est. Priority Date: 04/17/2002
  • Status: Active Grant
First Claim
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1. A microfluidic device, comprising:

  • a microchannel having an interior bounded by a side wall;

    a valve for regulating the flow of fluid through the microchannel, the valve comprising a gas-filled first reservoir, a fluid meniscus interfacing the reservoir and the interior and an actuator for varying the volume of the first reservoir to increase an internal pressure of the first reservoir to vary the flow of fluid through the microchannel; and

    a second reservoir for absorbing a pressure variation in the microchannel induced by the actuator.

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