Methods for reducing the risk of breast cancer in and improving the health of women
First Claim
1. A method for providing an individualized therapy for a menopausal or postmenopausal patient, wherein said method comprisesconducting a diagnostic mammogram;
- genotyping at least one enzyme system that regulates hormone biosynthesis and metabolism;
evaluating breast endocrine metabolism; and
based on the results of these tests, providing the individualized therapy to the patient.
1 Assignment
0 Petitions
Accused Products
Abstract
The subject invention provides methods for evaluating women in designing appropriate menopausal and postmenopausal therapies to match the particular needs of the individual. In one embodiment, the subject invention provides methods for evaluating particular factors in menopausal and postmenopausal women that are then taken into account in identifying a therapy program to promote good health and reduce the risk of any adverse health effects as a result of the therapy, specifically the role of hormone induced/associated breast cancer. More specifically, the subject invention includes methods for evaluating menopausal and postmenopausal women to determine whether hormone replacement therapy is appropriate in this regard, and if so, the specifics of how that therapy is to be administered. The subject invention, by incorporating various factors into a comprehensive, function breast hormone profile, allows for the identification of untreated women with estrogen-related metabolic abnormalities that may increase the risk of breast cancer. The subject invention determines specific therapies to correct and/or inhibit the aberrant biosynthetic pathways, and thus, the risk of cancer.
86 Citations
32 Claims
-
1. A method for providing an individualized therapy for a menopausal or postmenopausal patient, wherein said method comprises
conducting a diagnostic mammogram; -
genotyping at least one enzyme system that regulates hormone biosynthesis and metabolism;
evaluating breast endocrine metabolism; and
based on the results of these tests, providing the individualized therapy to the patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
-
-
29. A method for providing an individualized therapy for a menopausal or postmenopausal patient, wherein said method comprises gathering from the patient information regarding reproductive and family history;
-
conducting a comprehensive physical examination;
conducting a diagnostic mammogram;
administering to the patient a bone mineral density test;
genotyping breast estrogen receptor status;
evaluating breast endocrine metabolism;
conducting a breast metabolism biopsy; and
based on these results of these tests, providing the individualized therapy to the patient.
-
-
30. A method for providing an individualized therapy for a menopausal or postmenopausal patient, wherein said method comprises gathering from the patient information regarding reproductive and family history;
-
conducting a comprehensive physical examination;
conducting a diagnostic mammogram;
administering to the patient a bone mineral density test;
genotyping breast tissue expression levels of genes that determine the responsiveness of breast tissue to estrogen;
evaluating breast endocrine metabolism; and
based on the results of these tests, providing the individualized therapy to the patient. - View Dependent Claims (31, 32)
-
Specification