Multiparticulate modified release composition

CAFC
  • US 6,902,742 B2
  • Filed: 12/30/2002
  • Issued: 06/07/2005
  • Est. Priority Date: 11/02/1998
  • Status: Expired due to Term
First Claim
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1. A multiparticulate modified release composition comprising a first population of active ingredient-containing particles and at least one subsequent population of active ingredient-containing particles, the active ingredient contained in the first population being an opiate and the active ingredient in the subsequent population being an opiate or a non-opiate, wherein the subsequent population of active ingredient-containing particles further comprises a modified release coating or, alternatively or additionally, a modified release matrix material, such that the composition following oral delivery to a subject delivers the active ingredients of the first and subsequent populations in a pulsatile manner.

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