Substance delivery device

• US 6,908,448 B2
• Filed: 01/16/2003
• Issued: 06/21/2005
• Est. Priority Date: 08/24/2001
• Status: Expired due to Fees

• Current Assignee: Dermisonics, Inc.
• Original Assignee: Dermisonics, Inc.
• Inventors: Redding, Bruce K. Jr.
• Primary Examiner(s): Lucchesi, Nicholas D.
• Assistant Examiner(s): Thompson, Michael M.
• Application Number:
  US10/345,825
• Publication Number:
  US 20040024348A1
• Time in Patent Office: 887 Days
• Field of Search: 604/20, 604/22, 604/46, 604500-503, 607/115, 607/145, 607152-153, 424448-449
• US Class Current: 604/22
• CPC Class Codes: A61K 9/0009 involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis microelectromechanical systems A61K9/0097
• CPC Class Codes: A61K 9/7084 Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
• CPC Class Codes: A61M 2037/0007 having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
• CPC Class Codes: A61M 31/002 Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time artificial gland structures or devices A61F2/022; intra-uterine contraceptive devices A61F6/14; tampons for introducing into the vagina A61F13/20, A61L15/00; suppositories or bougies for intra-vaginal or intra-uterine application A61K9/02; physical forms of medicinal preparations for sustained or differential drug release A61K9/20, A61K9/50
• CPC Class Codes: A61M 37/0092 using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis

Abstract

A system being suitable for being secured substantially adjacent to a surface of a subject so as to effect delivery of at least one substance through the surface and into the subject. The system includes at least one aperture for receiving at least one ultrasonic transmission. The at least one substance is releasably secured substantially adjacent to the at least one aperture. A sonic member is disposed with respect to the at least one aperture so as to communicate the at least one transmission to the at least one substance so as to effect the delivery of the at least one substance through the surface of the subject.

Claims

1. A system being suitable for being secured substantially adjacent to a surface of a subject so as to effect delivery of at least one substance through said surface and into said subject, comprising:

at least one aperture for receiving at least one ultrasonic transmission, said at least one substance being releasably secured substantially adjacent to said at least one aperture;

a sonic member disposed with respect to said at least one aperture so as to communicate said at least one transmission to said at least one substance so as to effect said delivery of said at least one substance through said surface of said subject;

at least one ultrasonic transducer suitable for being positioned substantially adjacent to said aperture so as to emit ultrasonic transmissions through said aperture, and wherein a replaceable cap includes said substance, aperture and sonic member;

wherein said replaceable cap further comprises a pad substantially containing said substance and is positioned substantially between said aperture and sonic member; and

a semi-permeable film positioned substantially adjacent to said pad and forming an ultrasonically activated normally closed valving function to control delivery of said at least one substance through said surface of said subject.