Method of and apparatus for displaying and analyzing a physiological signal

• US 6,920,350 B2
• Filed: 08/06/2001
• Issued: 07/19/2005
• Est. Priority Date: 08/06/2001
• Status: Expired due to Fees

• Current Assignee: GE Medical Systems Information Technologies Incorporated (General Electric Company)
• Original Assignee: GE Medical Systems Information Technologies Incorporated (General Electric Company)
• Inventors: Xue, Joel Q., Reddy, Shankara B.
• Primary Examiner(s): Jastrzab, Jeffrey R.
• Application Number:
  US09/922,627
• Publication Number:
  US 20030028119A1
• Time in Patent Office: 1,443 Days
• Field of Search: 600/523, 600/508, 600/509, 600/524, 600/525, 600/481, 600/485, 600/800
• US Class Current: 600/523
• CPC Class Codes: A61B 5/339 Displays specially adapted therefor
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00

Abstract

A method of displaying a representation of a physiological signal produced by a patient. The method includes the acts of obtaining a portion of at least one physiological signal acquired from the patient, determining an area to display, and constructing a virtual image representing at least a portion of the patient. The virtual image including (M) polygonal areas. The method further includes transforming the obtained signal to a plurality of values, assigning each value to one of the (M) polygonal areas, assigning a visual characteristic to each polygonal area based in part on the assigned values, and displaying at least a portion of the virtual image including the assigned visual characteristics. The invention further provides a method of optimal feature selection for the classification of the physiological signals produced by a patient.

Claims

1. A method of displaying a representation of a physiological signal produced by an organ of interest of the patient, the method comprising the acts of:

obtaining a portion of at least one physiological signal, the obtaining act including acquiring the at least one physiological signal from the exterior of the patient;

determining a surface area of the exterior of the patient to display, wherein the surface area of the patient is different from the organ of interest;

constructing a three-dimensional virtual image of the surface area of the patient to be displayed and dividing the representative surface area into (M) polygonal areas;

transforming the obtained signal to a plurality of values;

assigning each value to one of the (M) polygonal areas;

assigning a visual characteristic to each polygonal area based in part on the assigned values; and

displaying at least a portion of the virtual image including the assigned visual characteristics.

2. A method as set forth in claim 1 wherein the act of obtaining a portion of at least one physiological signal includes the acts of placing a plurality of electrodes on the exterior of the patient and obtaining at least a portion of the multi-lead electrical signal acquired from the plurality of electrodes.

3. A method as set forth in claim 1 wherein the act of obtaining a portion of at least one physiological signal includes the act of obtaining at least a portion of a multi-lead electrocardiogram (ECG) acquired from the patient'"'"'s exterior.

4. A method as set forth in claim 3 wherein the multi-lead ECG is a twelve lead ECG.

5. A method as set forth in claim 4 wherein the obtained portion of the representative signal includes one data point for each lead.

6. A method as set forth in claim 4 wherein the obtained portion of the multi-lead ECG includes a plurality of data points representing a portion of the cardiac cycle.

7. A method as set forth in claim 6 wherein the obtained portion of multi-lead ECG includes the ST-wave of the cardiac cycle.

8. A method as set forth in claim 1 wherein the act of obtaining at least a portion of the at least one physiological signal includes the acts of attaching a sensor to the exterior of the patient and sensing the physiological signal with the sensor to obtain the at least one physiological signal.

9. A method as set forth in claim 8 wherein the sensor includes a plurality of electrodes.

11. A method as set forth in claim 1 wherein the virtual image represents at least a portion of the body surface of the patient.

12. A method as set forth in claim 1 wherein each polygonal area has a size and a shape, and wherein the sizes and shapes are equivalent areas.

13. A method as set forth in claim 1 wherein each polygonal area is a four-sided polygon.

14. A method as set forth in claim 1 wherein the act of assigning a visual characteristic to each polygonal area includes assigning a color to each polygonal area, based at least in part on the corresponding assigned value.

15. A method as set forth in claim 1 wherein the act of assigning a visual characteristic to each polygonal area includes assigning a character to each polygonal area, based at least in part on the corresponding assigned value.

17. A method as set forth in claim 1 wherein (M) is equal to one hundred ninety-two.

10. A method of displaying a representation of a physiological signal produced by an organ of interest of the patient, the method comprising the acts of:

obtaining a portion of at least one physiological signal acquired from the exterior of the patient, including the act of reading the at least one physiological signal from a memory device;

determining a surface area of the exterior of the patient to display, wherein the surface area of the patient is different from the organ of interest;

constructing a three-dimensional virtual image of the surface area of the patient to be displayed and dividing the representative surface area into (M) polygonal areas;

transforming the obtained signal to a plurality of values;

assigning each value to one of the (M) polygonal areas;

assigning a visual characteristic to each polygonal area based in part on the assigned values; and

displaying at least a portion of the virtual image including the assigned visual characteristics.

16. A method of displaying a representation of a physiological signal produced by an organ of interest of a patient, the method comprising the acts of:

obtaining a portion of at least one physiological signal, the obtaining act including acquiring the at least one physiological signal from a twelve lead electrocardiogram (ECG) acquired from the exterior of the patient, wherein the physiological signal includes one data point for each lead of the ECG;

determining an area to display;

constructing a virtual image including (M) polygonal areas;

transforming the data points of the twelve leads of the ECG to (M) values;

assigning each of the (M) value to one of the (M) polygonal areas such that each polygonal area has one of the (M) values;

assigning a visual characteristic to each polygonal area based in part on the assigned values; and

displaying at least a portion of the virtual image including the assigned visual characteristics.

18. A method of displaying a representation of an electrocardiogram (ECG), the method comprising the acts of:

obtaining at least a portion of a multi-lead ECG acquired from the patient'"'"'s exterior wherein the obtained portion of the ECG includes a plurality of data points for each lead representing a portion of the cardiac cycle;

determining an area to display;

constructing a virtual image including (M) polygonal areas;

transforming the obtain portion of the multi-lead ECG to (M) values;

assigning each value to one of the (M) polygonal areas, the assigning act resulting in each polygonal area having one of the (M) values;

assigning a visual characteristic to each polygonal area based in part on the assigned values; and

displaying at least a portion of the virtual image including the assigned visual characteristics.

19. A method as set forth in claim 18 wherein the number of obtained leads is twelve leads.

20. A method as set forth in claim 19 wherein (M) is equal to one hundred ninety-two.

21. A method as set forth in claim 18 wherein the act of obtaining at least a portion of a multi-lead ECG includes the acts of attaching a sensor to the patient'"'"'s exterior, sensing the ECG with the sensor, and creating the multi-lead ECG.

22. A method as set forth in claim 21 wherein the sensor includes a plurality of electrodes.

23. A method as set forth in claim 18 wherein the act of obtaining at least a portion of a multi-lead ECG includes the acts of reading at least a portion of the multi-lead ECG from a memory device.

24. A method as set forth in claim 18 wherein the virtual image is a three-dimensional surface area representing at least a portion of the patient.

25. A method as set forth in claim 18 wherein the (M) polygonal areas are regions on the three-dimensional surface area, wherein the (M) polygonal areas do not overlap, and wherein each polygonal area includes the same amount of area.

26. A method as set forth in claim 25 wherein each polygonal area is a four-sided polygon.

27. A method as set forth in claim 18 wherein the act of constructing a virtual image includes the acts of determining the portion of the patient to be represented, creating a multidimensional surface area representing the portion of the patient, determining the value of (M), and dividing the representative surface area into (M) polygonal areas.

28. A method as set forth claim 18 wherein the act of assigning a visual characteristic to each polygonal area includes assigning a color to each polygonal area based at least in part on the corresponding assigned value.

29. A method of analyzing a physiological signal produced by a patient and generating an optimal set of signals for particular diagnosis, the method comprising the acts of:

obtaining (N) voltages from (N) signals, respectively, the (N) signals representing the physiological sign, (N) being greater than one;

converting the (N) voltages to (M) values, where (M) is greater than (N);

repeating the act of obtaining (N) voltages (C) times, the repeating act resulting in (C) sets of (N) voltages;

repeating the act of converting the (N) voltages to (M) values for each set of (N) voltages, the repeating act resulting in (C) sets of (M) values; and

condensing the (C) sets of (M) values to one set of (M) values;

optimizing the one set of (M) values to (P) values, where (P) is less than (M).

30. A method as set forth in claim 29 and further comprising classifying the physiological signal with the (P) optimized values.

31. A method as set forth in claim 30 wherein the act of classifying the physiological signal includes the act of applying the (P) optimized values to a pattern recognition model for obtaining a classification output.

32. A method as set forth in claim 30 wherein the act of classifying the physiological signal includes the act of applying the (P) optimized values to a neural network for obtaining a classification output.

33. A method as set forth in claim 30 wherein the act of classifying the physiological signal includes the act of applying the (P) optimized values to a fuzzy algorithm for obtaining a classification output.

34. A method as set forth in claim 30 wherein the act of classifying the physiological signal includes the act of applying the (P) optimized values to a Bayesian decision logic for obtaining a classification output.

35. A method as set forth in claim 29 wherein (N) signals representing the physiological signal form a (N) multi-lead electrocardiogram.

36. A method as set forth in claim 35 wherein (N) is equal to twelve, (M) is equal to one hundred ninety-two, and (P) is equal to twelve.

37. A method as set forth in claim 29 wherein the physiological signal includes electrical signals that are generated by the patient'"'"'s heart in a cardiac cycle, and wherein the (C) sets of (N) voltages are an (N) multi-lead representation of a portion of the cardiac cycle.

38. A method as set forth in claim 29 wherein the act of obtaining the (N) voltages includes the acts of attaching a sensor to the patient'"'"'s exterior, sensing the physiological signal with the sensor to obtain (N) analog physiological signals, and sampling each signal to produce the (N) voltages.

39. A method as set forth in claim 38 wherein the sensor includes a plurality of electrodes.

40. A method as set forth in claim 29 wherein the act of obtaining (N) voltages includes the act of reading the (N) voltages from a memory device.

41. A method as set forth in claim 29 wherein the (C) sets of (M) values result in (M) virtual signals having (C) data points, and wherein the act of condensing the (C) sets of (M) values includes the act of integrating the (M) values over the (C) data points.

42. A method as set forth in claim 29 wherein the act of optimizing the (M) values to (P) values includes the acts of obtaining a database of previously recorded comparison values, computing a covariance matrix, and applying principal component analysis to the covariance matrix.

43. A method as set forth in claim 29 wherein the act of obtaining (N) voltages includes concurrently obtaining the (N) voltages from (N) signals, respectively.

44. A method as set forth in claim 29 wherein (N) is equal to twelve, (M) is equal to one hundred ninety-two, and (P) is equal to twelve.