Method and apparatus for monitoring biological abnormality and blood pressure

• US 6,923,769 B2
• Filed: 05/21/2002
• Issued: 08/02/2005
• Est. Priority Date: 05/31/2001
• Status: Expired due to Fees

• Current Assignee: DENSO Corporation, Junichiro Hayano
• Original Assignee: DENSO Corporation, Junichiro Hayano
• Inventors: Takeuchi, Satoshi, Nanba, Shinji, Nishii, Katsuyoshi, Kimura, Teiyuu, Hayano, Junichiro
• Primary Examiner(s): Nasser, Robert L.
• Application Number:
  US10/151,251
• Publication Number:
  US 20020183627A1
• Time in Patent Office: 1,169 Days
• Field of Search: 600/485, 600500-503, 600504-507
• US Class Current: 600/485
• CPC Class Codes: A61B 5/02125 of pulse wave propagation time
• CPC Class Codes: A61B 5/02255 the pressure being controlled by plethysmographic signals, e.g. derived from optical sensors
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light
• CPC Class Codes: A61B 5/0285 Measuring or recording phase velocity of blood waves
• CPC Class Codes: A61B 5/721 using a separate sensor to detect motion or using motion information derived from signals other than the physiological signal to be measured

Abstract

In a clinical and physiological abnormality monitoring apparatus, and blood pressure monitoring apparatus detects a blood pressure abnormality and the like of a body by employing a pulse wave signal. A frequency analysis is carried out with respect to a pulse wave signal, while this pulse wave signal corresponds to time sequential data of pulse waves. As a result, both a C-frequency component indicative of a fluctuation component of a base line of the pulse wave signal, and also an A-frequency component representative of the respective pulse waves are acquired. A ratio C/A of power of a peak contained in the C-frequency component with respect to power of a peak contained in the A-frequency component is calculated to determine abnormality of the blood pressure.

Claims

1. A clinical and physiological abnormality monitoring apparatus comprising:

means for detectiong vasomotion of a body in a percutaneous manner; and

means for determining a clinical and physiological abnormality upon the detected vasomotion,

wherein the detecting means detects a change contained in a blood flow condition of the blood vessels in the percutaneous manner so as to acquire a fluctuation of the blood flow condition caused by the vasomotion, the acquired fluctuation being used to determine the clinical and physiological abnormality.

2. A clinical and physiological abnormality monitoring apparatus as in claim 1, wherein:

the detecting means detects frequency component corresponding to the fluctuation of the blood flow condition, which is lower than a frequency component corresponding to a pulse interval.

3. A clinical and physiological abnormality monitoring apparatus as in claim 1, wherein:

the detecting means detects both frequency components corresponding to the pulse interval and corresponding to the fluctuation of the blood flow condition, which is lower than the frequency component corresponding to the pulse interval, the detected frequency components being used to determine the clinical and physiological abnormality.

4. A clinical and physiological abnormality monitoring apparatus as in claim 1, wherein:

the detecting means detects a change contained in fluctuations of the blood flow condition after the measuring operation is commenced, the detected change contained in the fluctuations being used to determine the clinical and physiological abnormality.

5. A clinical and physiological abnormality monitoring apparatus as in claim 1, wherein:

the detecting means detects a change contained in fluctuations of the blood flow condition before a predetermined period is detected, the detected change being used to determine the clinical and physiological abnormality.

6. A clinical and physiological abnormality monitoring apparatus as in claim 1, wherein:

the detecting means includes a blood flow condition detecting apparatus unit for acquiring the fluctuation of the blood flow condition.

7. A clinical and physiological abnormality monitoring apparatus as in claim 1, wherein:

the determining means determines the clinical and physiological abnormality based upon both the fluctuation of the blood flow condition and body motion.

8. A clinical and physiological abnormality monitoring apparatus as in claim 7, wherein:

the detecting means includes a blood flow condition detecting apparatus unit for detecting the fluctuation of the blood flow condition; and

a body motion detecting apparatus unit for detecting the body motion.

9. A clinical and physiological abnormality monitoring apparatus as in claim 1, wherein:

the detecting means acquires a C-frequency component corresponding to the fluctuation of the blood flow condition from a measured pulse wave signal, the acquired C-frequency component being used to determine the clinical and physiological abnormality.

10. A clinical and physiological abnormality monitoring apparatus as in claim 9, wherein:

the C-frequency component of a predetermined frequency range corresponds to a frequency component indicative of the fluctuation of the pulse wave signals in which the pulse wave is continued.

11. A clinical and physiological abnormality monitoring apparatus as in claim 9, wherein:

the C-frequency component of the predetermined frequency range corresponds to a frequency component lower than an A-frequency component of a frequency range corresponding to the respective pulse waves.

12. A clinical and physiological abnormality monitoring apparatus as in claim 11, wherein:

the determining means compares the value C equivalent to the C-frequency component with a value A equivalent to the A-frequency component.

13. A clinical and physiological abnormality monitoring apparatus as in claim 12, wherein:

the determining means determines the clinical and physiological abnormality based upon a ratio C/A of the value C equivalent to the C-frequency component with respect to the value A equivalent to the A-frequency component.

14. A clinical and physiological abnormality monitoring apparatus as in claim 12, wherein:

the determining means determines the clinical and physiological abnormality based upon a change amount of ratios C/A of the value C equivalent to the C-frequency component with respect to the value A equivalent to the A-frequency component.

15. A clinical and physiological abnormality monitoring apparatus as in claim 9, wherein:

the determining means compares a value C equivalent to the C-frequency component with a predetermined threshold value.

16. A clinical and physiological abnormality monitoring apparatus as in claim 9, wherein:

the detecting means acquires the C-frequency component in a frequency range lower than about 0.5 Hz.

17. A clinical and physiological abnormality monitoring apparatus as in claim 16, wherein:

the detecting means acquires the C-frequency component in a frequency range lower than about 0.25 Hz.

18. A clinical and physiological abnormality monitoring apparatus as in claim 9, wherein:

the detecting means employs, as the value C equivalent to the C-frequency component, a maximum peak value in the predetermined frequency range.

19. A clinical and physiological abnormality monitoring apparatus as in claim 9, wherein:

the detecting means employs, as the value C equivalent to the C-frequency component, a peak value which is larger than a threshold value in the predetermined frequency range.

20. A clinical and physiological abnormality monitoring apparatus as in claim 9, wherein:

the detecting means employs, as the value C equivalent to the C-frequency component, an integral value in the predetermined frequency range.

21. A clinical and physiological abnormality monitoring apparatus as in claim 9, wherein:

the detecting means includes a plurality of pulse wave sensors.

22. A clinical and physiological abnormality monitoring apparatus as in claim 21, wherein:

the detecting means employs pulse wave signals derived from the plurality of pulse wave sensors larger than a predetermined number.

23. A clinical and physiological abnormality monitoring apparatus as in claim 21, wherein:

the pulse waves are measured at a clinical and physiological area larger than about 5 mm 2 by using the pulse wave sensor.

24. A clinical and physiological abnormality monitoring apparatus as in claim 1, further comprising:

notifying means for notifying the clinical and physiological abnormality.

25. A clinical and physiological abnormality monitoring apparatus as in claim 1, wherein:

the clinical and physiological abnormality corresponds to a blood pressure abnormality of the body.

26. A blood pressure monitoring apparatus comprising:

means for detecting vasomotion of a body in a percutaneous manner; and

means for measuring a blood pressure based upon the detected vasomotion,

wherein the detecting means detects a change contained in a blood flow condition of the blood vessel in the percutaneous manner so as to acquire a fluctuation of the blood flow condition caused by the vasomotion, the acquired fluctuation being used to measure the blood pressure.

27. A blood pressure monitoring apparatus as in claim 26, wherein:

the detecting means detects a frequency component corresponding to the fluctuation of the blood flow condition, which is lower than a frequency component corresponding to a pulse interval, the detected frequency component being used to measure the blood pressure.

28. A blood pressure monitoring apparatus as in claim 26, wherein:

the detecting means detects both frequency components corresponding to the pulse interval and corresponding to the fluctuation of the blood flow condition, which is lower than the frequency component corresponding to the pulse interval, the detected both frequency components being used to measure the blood pressure.

29. A blood pressure monitoring apparatus as in claim 28, wherein:

the measuring means measures the blood pressure based upon a ratio of a frequency component equivalent to a pulse interval with respect to a frequency component equivalent to the fluctuation of the blood flow condition, which is lower than the frequency component.

30. A blood pressure monitoring apparatus as in claim 26, wherein:

the detecting means detects a change contained in fluctuations of the blood flow condition after a measuring operation is commenced, the detected change contained in the fluctuations being used to measure the blood pressure.

31. A blood pressure monitoring apparatus as in claim 26, wherein:

the detecting means detects a change contained in fluctuations of the blood flow condition before a predetermined period, the detected change contained in the fluctuations being used to measure the blood pressure.

32. A blood pressure monitoring apparatus as in claim 26, wherein:

the detecting means variably sets a threshold value used to execute the blood pressure measurement.

33. A blood pressure monitoring apparatus as in claim 26, wherein:

the detecting means automatically adjusts a threshold value used to execute the blood pressure measurement based upon a blood pressure value which has already been measured.

34. A blood pressure monitoring apparatus as in claim 26, wherein:

a condition for the blood pressure measurement is set based upon both the fluctuation of the blood flow condition and body motion.

35. A blood pressure monitoring apparatus as in claim 26, wherein:

a change contained in the blood flow condition, an analysis result thereof, and the measured blood pressure value are externally outputted.

36. A blood pressure monitoring apparatus as in claim 26, further comprising:

the detecting means includes a blood flow condition detecting apparatus unit for acquiring the fluctuation of the blood flow condition.

37. A blood pressure monitoring apparatus as in claim 26, wherein:

the measuring means includes a blood pressure measuring apparatus unit for performing the blood pressure measurement.

38. A blood pressure monitoring apparatus as in claim 37, wherein:

the blood pressure measuring apparatus unit has a cuff.

39. A blood pressure monitoring apparatus as in claim 38, wherein:

a cuff-pressure applying amount of the blood pressure measuring apparatus unit used when a subsequent blood pressure measurement is carried out is automatically adjusted based upon the measured blood pressure value.

40. A blood pressure monitoring apparatus as in claim 26, wherein:

the detecting means includes a blood flow condition detecting apparatus unit for acquiring the fluctuation of the blood flow condition; and

the measuring means includes a blood pressure measuring apparatus unit for performing the blood pressure measurement.

41. A blood pressure monitoring apparatus as in claim 40, further comprising:

an alarm issuing unit for issuing an alarm in the case that an abnormality of the blood pressure is detected.

42. A blood pressure monitoring apparatus as in claim 26, wherein:

the detecting means includes a blood flow condition detecting apparatus unit for acquiring the fluctuation of the blood flow condition; and

the measuring means includes an alarm issuing unit for issuing an alarm in the case that an abnormality of the blood pressure is detected.

43. A blood pressure monitoring apparatus as in claim 26, wherein:

the detecting means includes a blood flow condition detecting apparatus unit for detecting the fluctuation of the blood flow condition, and a body motion detecting apparatus unit for detecting the body motion.

44. A blood pressure monitoring apparatus as in claim 26, wherein:

the detecting means includes a plurality of detecting units for detecting the change contained in the blood flow condition.

45. A blood pressure monitoring apparatus as in claim 26, wherein:

the measuring means stops measuring a blood pressure value higher than a predetermined upper-limit blood pressure.