Method and apparatus to minimize effects of a cardiac insult

• US 7,010,345 B2
• Filed: 10/26/2001
• Issued: 03/07/2006
• Est. Priority Date: 10/26/2000
• Status: Expired due to Fees

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Zhou, Xiaohong, Mullen, Thomas J., King, Gary W., Hill, Michael R. S.
• Primary Examiner(s): Pezzuto, Robert E.
• Assistant Examiner(s): Oropeza, Frances P.
• Application Number:
  US09/999,723
• Publication Number:
  US 20020143369A1
• Time in Patent Office: 1,593 Days
• Field of Search: 600/373, 600/377, 600/509, 600/515, 600/516, 600/518, 600/519, 600/521, 607/6, 607/7, 607/9, 607/10, 607/11, 607/14, 607/25, 607/48, 607/117, 607/118
• US Class Current: 607/10
• CPC Class Codes: A61N 1/36114 Cardiac control, e.g. by vagal stimulation stimulating the heart A61N1/362
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy

Abstract

A method and apparatus are provided for protecting cardiac tissue from insult. The method comprises identifying the occurrence of an insult, such as a heart attack, and delivering electrical stimulation to one or more predetermined nerves in a patient'"'"'s body in response to identifying the occurrence of the insult. The stimulation may be provided at the spinal canal or on the chest wall of the patient through cutaneous electrodes.

Claims

1. A method for protecting cardiac tissue from a myocardial insult resulting in necrosis of myocardial tissue, comprising:

identifying an occurrence of a myocardial insult capable of resulting in necrosis of myocardial tissue; and

automatically delivering electrical stimulation cutaneously adjacent to one or more of the T1–

T12 vertebrae or at upper cervical levels C1–

C4 over the back of the head and neck in a patient'"'"'s body using one or more electrodes positioned adjacent an external surface of the body in order to avoid necrosis of myocardial tissue due to the insult, wherein said one or more electrodes are spaced from myocardial tissue of the patient.

2. The method of claim 1, wherein identifying the occurrence of the insult further comprises identifying one or more symptoms of a heart attack.

3. The method of claim 1, further comprising identifying the severity of the insult.

4. The method of claim 3, wherein delivering electrical stimulation further comprises delivering electrical stimulation having an intensity based on the identified severity of the insult.

5. The method of claim 1, wherein the delivering electrical stimulation further comprises:

storing data descriptive of the electrical stimulation;

analyzing the effectiveness of the electrical stimulation; and

adjusting the delivery of electrical stimulation in a subsequent delivery of electrical stimulation.

6. The method of claim 1, wherein delivering electrical stimulation further comprises delivering electrical stimulation for a period of time extending beyond a cessation of the insult.

7. The method of claim 1, wherein delivering electrical stimulation further comprises delivering electrical stimulation for a preselected duration of time.

8. The method of claim 1, wherein identifying the occurrence of the insult further comprises determining that a defibrillation shock has been administered.

9. The method of claim 1, wherein identifying the occurrence of the insult further comprises detecting myocardial ischemia.

10. The method of claim 1, wherein identifying the occurrence of the insult further comprises detecting an arrhythmic event.

11. The method of claim 1, wherein identifying the occurrence of the insult further comprises detecting non-sustained ventricular tachycardia.

12. The method of claim 1, wherein identifying the occurrence of the insult further comprises detecting precursors to a ventricular arrhythmia.

13. The method of claim 1, and further comprising sensing a physiologic parameter;

and

adjusting delivery of electrical stimulation based on the sensed physiologic parameter.

14. The method of claim 13, wherein multiple physiologic parameters are sensed;

and wherein delivery of electrical stimulation is adjusted based on the multiple physiologic parameters.

15. The method of claim 14, and further comprising obtaining an indication based on a weighting of the multiple physiologic parameters;

and

adjusting delivery of the electrical stimulation based on the indication.

16. The method of claim 15, and further comprising providing a patient notification indicative of the cardiac insult.

17. An apparatus for protecting cardiac tissue from a myocardial insult resulting in necrosis of myocardial tissue, comprising:

at least one electrode positionable adjacent an external surface of a body and cutaneously adjacent to one or more of the T1–

T12 vertebrae or at upper cervical levels C1–

C4 over the back of the head and neck proximate to nerve tissue and spaced from myocardial tissue; and

a controller adapted to identify a cardiac insult and to automatically deliver electrical stimulation to the at least one electrode in order to avoid necrosis of myocardial tissue due to the insult.

18. The apparatus of claim 17, further comprising memory adapted to store data descriptive of the electrical stimulation, and wherein the controller is adapted to analyze the stored data and adjust electrical stimulation in response thereto.

19. The apparatus of claim 17, further comprising a sensor configured to detect a physiologic condition representative of an operating characteristic of the patients heart, and wherein the controller is adapted to deliver electrical stimulation to the at least one electrode based on an indication of the physiologic condition.

20. The apparatus of claim 19, wherein the controller includes a circuit to control delivery of electrical stimulation to the electrodes for a preselected duration of time.

21. A computer readable medium for storing instructions for performing a computer-implemented method to protect cardiac tissue from a myocardial insult resulting in necrosis of myocardial tissue, comprising:

software encoded instructions for identifying an occurrence of a myocardial insult; and

software encoded instructions automatically delivering electrical stimulation using one or more electrodes positioned adjacent an external surface of the body in order to avoid necrosis of myocardial tissue due to the insult.

22. A medium according to claim 21, wherein the software encoded instructions for identifying the occurrence of the insult further comprises software encoded instructions for identifying one or more symptoms of a heart attack.

23. A medium according to claim 21, further comprising identifying the severity of the insult which produces said necrosis of myocardial tissue.

24. A medium according to claim 23, wherein the software encoded instructions for delivering electrical stimulation further comprises software encoded instructions for delivering electrical stimulation having an intensity based on the identified severity of the insult.

25. A medium according to claim 21, wherein the software encoded instructions for delivering electrical stimulation further comprises:

software encoded instructions for storing data descriptive of the electrical stimulation;

software encoded instructions for analyzing the effectiveness of the electrical stimulation; and

software encoded instructions for adjusting the delivery of electrical stimulation in a subsequent delivery of electrical stimulation.