Inhaled insulin dosage control delivery enhanced by controlling total inhaled volume

  • US 7,028,686 B2
  • Filed: 11/04/2003
  • Issued: 04/18/2006
  • Est. Priority Date: 01/29/1993
  • Status: Expired due to Fees
First Claim
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1. A method of administering a formulation to a human patient by inhalation, comprising:

  • (a) aerosolizing a formulation comprised of a pharmaceutically active compound wherein the aerosol is comprised of particles having a diameter in a range of about 0.5 to 6.0 microns;

    (b) inhaling the aerosolized formulation with a known volume of air, (c) repeating (a) and (b) a plurality of times over a period of time;

    wherein the known volume of air with aerosolized formulation inhaled in each step (b) is substantially the same for each step (b) and further wherein the inhaled volume of air in step (b) is determined by the patient inhaling maximally which inhaling maximally is repeated for each step (b).

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