Gateway platform for biological monitoring and delivery of therapeutic compounds
First Claim
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1. A system for monitoring physiological status of a mammalian subject, comprising:
- a. one or more biointerface heads (BIH), each comprising one or both of a sensor for measuring a physiological parameter and a device for therapeutic compound delivery, at least one of said biointerface heads being implanted subdermally and configured to communicate data and a BIH identifier;
b. at least one control and communication module (CCM) attached to an external surface of said subject and storing a CCM identifier and which is linked to at least one biointerface head to receive said data and said BIH identifier, wherein said control and communication module processes data from at least one biointerface head;
c. at least one data collection unit (DCU) which receives data and said identifiers from the control and communication module; and
d. a remote database management system which receives data from the at least one data collection unit and processes said data.
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Abstract
The invention relates to methods and devices for remote or distributed continuous monitoring of physiologically relevant states. The invention provides for methods to automatically detect deviations or other states in physiological parameters and automatically alert a measured subject, user or other authorized party. The device provides for a universal platform for sensors, and further provides for the automatic compensation or distribution of devices or bioactive agents at appropriate levels and/or intervals in response to deviations or other states sensed in various physiological parameters.
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12 Claims
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1. A system for monitoring physiological status of a mammalian subject, comprising:
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a. one or more biointerface heads (BIH), each comprising one or both of a sensor for measuring a physiological parameter and a device for therapeutic compound delivery, at least one of said biointerface heads being implanted subdermally and configured to communicate data and a BIH identifier; b. at least one control and communication module (CCM) attached to an external surface of said subject and storing a CCM identifier and which is linked to at least one biointerface head to receive said data and said BIH identifier, wherein said control and communication module processes data from at least one biointerface head; c. at least one data collection unit (DCU) which receives data and said identifiers from the control and communication module; and d. a remote database management system which receives data from the at least one data collection unit and processes said data. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A system comprising:
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a subdermal physiological parameter sensor to measure a physiological parameter of a mammalian subject and to generate measurement information based on the measurements; a mounting structure that anchors said system to a dermal layer; a flexible transdermal conduit attached to said mounting structure at or near a first end, wherein said transdermal conduit is in contact with a sensor assembly; a sensor mounting head, wherein said sensor mounting head is attached to a second end of said transdermal conduit; a biofluid access port within said sensor mounting head, the biofluid access port further comprising microstructures allowing biofluid flow into the transdermal conduit to contact the sensor assembly and block transmission of external pathogens into a subject; a control and communication module in data communication with the physiological parameter sensor to receive the measurement information from the physiological parameter sensor, the control and communication module including signal processing circuitry to generate and transmit a first signal based on the measurement information. - View Dependent Claims (10, 11, 12)
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Specification