Fluorescent dyed lubricant for medical devices
First Claim
1. A method for detecting the presence and uniformity of a lubricious coating on a medical device comprising the steps of:
- a) preparing a mixture of at least one fluorescing agent which is a xanthene, a triarylmethane or mixture thereof and at least one lubricant;
b) applying said mixture to the surface of a medical device to form a coating capable of exhibiting fluorescence; and
c) subjecting the surface of the medical device to a source of energy capable of inducing a fluorescent emission; and
d) observing the fluorescent emission to determine the location, uniformity or both of said lubricant.
2 Assignments
0 Petitions
Accused Products
Abstract
A composition and method for detecting the presence, location and uniformity of a lubricious coating on a medical device. The method includes the steps of preparing a mixture of a biocompatible hydrophilic fluorescent dye and a hydrophobic lubricant, applying the mixture to the surface of a medical device to form a coating capable of exhibiting fluorescence, and subjecting the surface of the medical device to a source of energy capable of inducing a fluorescent emission. The coating composition may further comprise a surfactant. This method finds particular utility for catheters, especially stent delivery catheters.
16 Citations
15 Claims
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1. A method for detecting the presence and uniformity of a lubricious coating on a medical device comprising the steps of:
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a) preparing a mixture of at least one fluorescing agent which is a xanthene, a triarylmethane or mixture thereof and at least one lubricant;
b) applying said mixture to the surface of a medical device to form a coating capable of exhibiting fluorescence; and
c) subjecting the surface of the medical device to a source of energy capable of inducing a fluorescent emission; and
d) observing the fluorescent emission to determine the location, uniformity or both of said lubricant. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method for detecting the presence and uniformity of a lubricious coating on a medical device comprising the steps of:
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a) preparing a mixture of at least one fluorescing agent and mixtures thereof and at least one lubricant using a cosolvent blend;
b) applying said mixture to the surface of a medical device to form a coating capable of exhibiting fluorescence; and
c) subjecting the surface of the medical device to a source of energy capable of inducing a fluorescent emission; and
d) observing the fluorescent emission to determine the location, uniformity or both of said lubricant. - View Dependent Claims (13, 14)
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15. A method for detecting the presence and uniformity of a lubricious coating on a medical device comprising the steps of:
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a) preparing a mixture of at least one hydrophilic fluorescing agent and mixtures thereof and at least one lubricant;
b) applying said mixture to the surface of a medical device to form a coating capable of exhibiting fluorescence; and
c) subjecting the surface of the medical device to a source of energy capable of inducing a fluorescent emission; and
d) observing the fluorescent emission to determine the location, uniformity or both of said lubricant.
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Specification