Inhalable powder containing tiotropium

  • US 7,070,800 B2
  • Filed: 10/11/2001
  • Issued: 07/04/2006
  • Est. Priority Date: 10/12/2000
  • Status: Active Grant
First Claim
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1. An inhalable powder comprising 0.04 to 0.8% of tiotropium in admixture with a physiologically acceptable excipient, wherein the excipient consists of a mixture of coarser excipient with an average particle size of 15 to 80 μ

  • m and finer excipient with an average particle size of 1 to 9 μ

    m, the proportion of the finer excipient constituting 1 to 20% of the total amount of excipient, wherein the inhalable proportion of active substance is released reproducibly in low variability amounts when administered to a patent.

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