Method for delivering energy to tissue and apparatus

• US 7,074,233 B1
• Filed: 06/25/2004
• Issued: 07/11/2006
• Est. Priority Date: 03/28/2002
• Status: Expired due to Term

• Current Assignee: BioTex Incorporated, Board of Regents of the University of Texas System (University of Texas System)
• Original Assignee: BioTex Incorporated, Board of Regents of the University of Texas System (University of Texas System)
• Inventors: Gowda, Ashok, McNichols, Roger J., Motamedi, Massoud, Pasricha, Pankaj J.
• Primary Examiner(s): Johnson, III, Henry M
• Application Number:
  US10/877,811
• Time in Patent Office: 746 Days
• Field of Search: 128/898, 607/89
• US Class Current: 607/89
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2017/22051 with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation A61B2017/22048, A61B2017/3486 take precedence
• CPC Class Codes: A61B 2018/00023 closed, i.e. without wound contact by the fluid
• CPC Class Codes: A61B 2018/2261 with scattering, diffusion or dispersion of light

Abstract

Disclosed is a method for delivering energy to a tissue. The method includes providing an apparatus which includes an energy delivery component and an inflatable member disposed around the energy delivery component. At a minimum, the inflatable member is constructed of a flexible inner wall and a flexible outer wall, which, taken together, enclose a cavity therebetween. The inflatable member is expanded such that the inflatable member'"'"'s outer wall contacts the tissue'"'"'s surface. Cooling fluid is disposed in the cavity, and energy is delivered to the energy delivery component so that at least a portion of the energy delivered to the energy delivery component passes through the inflatable member'"'"'s inner wall, through the cooling fluid disposed in the cavity, through the inflatable member'"'"'s outer wall, and into the tissue. Various apparatus suitable for use in delivering energy to tissues are also disclosed, as is a method for treating GERD or otherwise reducing reflux of a subject'"'"'s stomach contents into the subject'"'"'s esophagus.

Claims

1. A method for delivering energy to a tissue having a tissue surface, said method comprising:

providing an apparatus comprising an energy delivery component and an inflatable member disposed around the energy delivery component, wherein the inflatable member comprises an inner wall and an outer wall, wherein the inflatable member'"'"'s inner wall is flexible, wherein the inflatable member'"'"'s outer wall is flexible, and wherein the inflatable member'"'"'s inner wall and the inflatable member'"'"'s outer wall enclose a cavity therebetween;

expanding the inflatable member such that the inflatable member'"'"'s outer wall contacts the tissue surface;

disposing a cooling fluid in the cavity; and

delivering energy to the energy delivery component so that at least a portion of the energy delivered to the energy delivery component passes through the inflatable member'"'"'s inner wall, through the cooling fluid disposed in the cavity, through the inflatable member'"'"'s outer wall, and into the tissue.

2. A method according to claim 1, wherein the tissue is a lower esophageal sphincter.

3. A method according to claim 1, wherein the energy delivery component is an optical waveguide coupled to a light source.

4. A method according to claim 1, wherein the energy delivery component is fiber optic coupled to a monochromatic light source.

5. A method according to claim 1, wherein the energy delivery component is fiber optic coupled to a laser light source.

6. A method according to claim 1, wherein the tissue comprises a surface tissue layer and one or more subsurface tissue layers lying beneath the surface tissue layer and wherein the energy is selected so as to be preferentially absorbed by at least one of the subsurface tissue layers.

7. A method according to claim 1, wherein the tissue comprises a mucosal layer and a muscle layer lying beneath the mucosal layer and wherein the energy is selected so as to be preferentially absorbed by the muscle layer.

8. A method according to claim 1, wherein said disposing a cooling fluid in the cavity is carried out by circulating the cooling fluid through the cavity during said delivering.

9. A method according to claim 1, wherein said delivering is carried out for a period of time sufficient to produce a lesion in an least a portion of the tissue.

10. A method according to claim 1, wherein the tissue comprises a mucosal layer and a muscle layer lying beneath the mucosal layer, wherein said delivering is carried out under conditions effective to produce a lesion in at least a portion of the muscle layer, and wherein the lesion is substantially confined to the muscle layer.

11. A method according to claim 1 further comprising:

detecting a change in a property of the tissue resulting from energy delivered to the tissue by the apparatus.

12. A method for delivering energy to a tissue comprising a surface tissue layer and one or more subsurface tissue layers lying beneath the surface tissue layer, said method comprising:

cooling at least the tissue'"'"'s surface tissue layer with a cooling fluid; and

exposing the tissue to laser energy such that the laser energy is preferentially absorbed by at least one of the subsurface tissue layers.

13. A method according to claim 12, wherein the tissue comprises a surface tissue layer, a mucosal layer lying beneath the surface tissue layer, and a muscle layer lying beneath the mucosal layer and wherein the laser energy is selected so as to be preferentially absorbed by the muscle layer.